Autophagy

Autophagy

自噬

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion 246
Autophagy pathway: Cellular and molecular mechanisms 186
Autophagy balances inflammation in innate immunity 80
METTL3 and ALKBH5 oppositely regulate m(6)A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes 55
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke 53
Autophagy and inflammation in chronic respiratory disease 52
Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells 47
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration 42
Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles 41
PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury 38
BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation 38
Actin filaments are dispensable for bulk autophagy in plants 36
Inflammatory signaling cascades and autophagy in cancer 34
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome 33
Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype 33
Mechanisms and context underlying the role of autophagy in cancer metastasis 28
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance 28
Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2) 28
Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations 27
Autophagy-dependent secretion: mechanism, factors secreted, and disease implications 26
Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models 26
Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A 25
Thyroid hormone (T-3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy 24
Mitophagy and NAD(+) inhibit Alzheimer disease 24
Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis 23
Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys 23
Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease 22
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency 22
Ion channels in the regulation of autophagy 20
Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion 20
Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs 20
Viral strategies for triggering and manipulating mitophagy 20
Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth 20
Alborixin clears amyloid-beta by inducing autophagy through PTEN-mediated inhibition of the AKT pathway 20
Autophagy dictates metabolism and differentiation of inflammatory immune cells 20
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis 20
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis 19
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis 19
Parallel damage in mitochondria and lysosomes is an efficient way to photoinduce cell death 19
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells 18
Autophagy regulates glucose-mediated root meristem activity by modulating ROS production in Arabidopsis 18
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition 18
Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers 18
The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis 18
Emerging roles for TFEB in the immune response and inflammation 18
Autophagy and innate immunity: Insights from invertebrate model organisms 18
Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases 17
MTA1 is a novel regulator of autophagy that induces tamoxifen resistance in breast cancer cells 17
Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma 17
ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction 17