Biotechnology Progress

Biotechnology Progress

生物技术进展

  • 3区 中科院分区
  • Q3 JCR分区

高引用文章

文章名称 引用次数
Recent advances on sources and industrial applications of lipases 46
Kinetic Resolution of Drug Intermediates Catalyzed by Lipase B from Candida Antarctica Immobilized on Immobead-350 19
Biogenic synthesis of copper oxide nanoparticles using olea europaea leaf extract and evaluation of their toxicity activities: An in vivo and in vitro study 16
Cell culture media for recombinant protein expression in Chinese hamster ovary (CHO) cells: History, key components, and optimization strategies 15
Polyhydroxyalkanoates: Properties and chemical modification approaches for their functionalization 14
Silver-gold alloy nanoparticles biofabricated by fungal xylanases exhibited potent biomedical and catalytic activities 13
Case study: The characterization and implementation of dielectric spectroscopy (biocapacitance) for process control in a commercial GMP CHO manufacturing process 12
beta-Mannanase production and kinetic modeling from carob extract by using recombinant Aspergillus sojae 12
Saponins and microbial biosurfactants: Potential raw materials for the formulation of cosmetics 12
Experience with Host Cell Protein Impurities in Biopharmaceuticals 12
Tissue and organ decellularization in regenerative medicine 11
Photobioreactor Cultivation Strategies for Microalgae and Cyanobacteria 11
Enzymatic Synthesis of Ethyl Esters from Waste Oil Using Mixtures of Lipases in a Plug-Flow Packed-Bed Continuous Reactor 10
Real-Time Monitoring of Antibody Glycosylation Site Occupancy by In Situ Raman Spectroscopy During Bioreactor CHO Cell Cultures 9
Design of experiments applications in bioprocessing: Chromatography process development using split design of experiments 9
Development of generic raman models for a GS-KOTM CHO platform process 9
Isolation of two novel purple naphthoquinone pigments concomitant with the bioactive red bikaverin and derivates thereof produced by Fusarium oxysporum 8
Decision Tree-PLS (DT-PLS) algorithm for the development of process: Specific local prediction models 8
Imaging brain tissue slices with terahertz near-field microscopy 8
Probing lactate metabolism variations in large-scale bioreactors 8
Cell Pretreatment with Ethylenediaminetetraacetic Acid for Selective Extraction of C-Phycocyanin with Food Grade Purity 8
Lactic acid production from sugarcane bagasse hydrolysates by Lactobacillus pentosus: Integrating xylose and glucose fermentation 7
A novel mammalian cell line development platform utilizing nanofluidics and optoelectro positioning technology 7
Cooperativity of covalent attachment and ion exchange on alcalase immobilization using glutaraldehyde chemistry: Enzyme stabilization and improved proteolytic activity 6
Cross-linked enzyme aggregates of recombinant Candida antarctica lipase B for the efficient synthesis of olvanil, a nonpungent capsaicin analogue 6
A new flow cell and chemometric protocol for implementing in-line Raman spectroscopy in chromatography 6
A microfluidic chip with gravity-induced unidirectional flow for perfusion cell culture 6
Hydrolysis of Lipid-Extracted Chlorella vulgaris by Simultaneous Use of Solid and Liquid Acids 6
Lactobacillus pentosus CECT 4023 T co-utilizes glucose and xylose to produce lactic acid from wheat straw hydrolysate: Anaerobiosis as a key factor 6
Prediction of recombinant protein production by Escherichia coli derived online from indicators of metabolic burden 6
Achieving greater efficiency and higher confidence in single-cell cloning by combining cell printing and plate imaging technologies 6
Continuous precipitation for monoclonal antibody capture using countercurrent washing by microfiltration 6
Amberlite IRA 900 versus calcium alginate in immobilization of a novel, engineered beta-fructofuranosidase for short-chain fructooligosaccharide synthesis from sucrose 6
Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins 6
Monitoring mAb cultivations with in-situ raman spectroscopy: The influence of spectral selectivity on calibration models and industrial use as reliable PAT tool 6
In vitro cytotoxic activity of microalgal extracts loaded nano-micro particles produced via electrospraying and microemulsion methods 6
Immobilization on octyl-agarose beads and some catalytic features of commercial preparations of lipase a from Candida antarctica (Novocor ADL): Comparison with immobilized lipase B from Candida antarctica 6
Extraction of bioactive compounds against cardiovascular diseases from Lentinula edodes using a sequential extraction method 6
Establishment of a CFD-Based k(L)a Model in Microtiter Plates to Support CHO Cell Culture Scale-Up during Clone Selection 6
Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins 5
Effective bioreactor pH control using only sparging gases 5
Sodium Bicarbonate-Gelled Chitosan Beads as Mechanically Stable Carriers for the Covalent Immobilization of Enzymes 5
Characterization of Biogenic Fe (III)-Binding Exopolysaccharide Nanoparticles Produced by Ralstonia Sp. SK03 5
Effects of cholinium-based ionic liquids on Aspergillus niger lipase: Stabilizers or inhibitors 5
Inline noninvasive Raman monitoring and feedback control of glucose concentration during ethanol fermentation 5
Glucose monitoring and adaptive feeding of mammalian cell culture in the presence of strong autofluorescence by near infrared Raman spectroscopy 5
Shift to high-intensity, low-volume perfusion cell culture enabling a continuous, integrated bioprocess 5
Effects of phosphonium-based ionic liquids on the lipase activity evaluated by experimental results and molecular docking 5
Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not 5
Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality 5