Cell Death And Differentiation

Cell Death And Differentiation

细胞死亡和分化

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高引用文章

文章名称 引用次数
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 617
BCL-2 family proteins: changing partners in the dance towards death 144
How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? 129
The BCL-2 arbiters of apoptosis and their growing role as cancer targets 94
Mutant p53 as a guardian of the cancer cell 87
Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM 82
Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2 alpha-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy 65
To NET or not to NET: current opinions and state of the science regarding the formation of neutrophil extracellular traps 62
MOMP, cell suicide as a BCL-2 family business 62
Autophagy-dependent cell death 60
Why do BCL-2 inhibitors work and where should we use them in the clinic? 57
Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion 57
Pyroptosis versus necroptosis: similarities, differences, and crosstalk 54
Mechanisms of transcriptional regulation by p53 53
Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes 47
Anti-apoptotic BCL-2 family members in development 45
LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein 43
miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma 42
Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications 42
STING directly activates autophagy to tune the innate immune response 41
Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA 40
Why are there hotspot mutations in the TP53 gene in human cancers? 39
The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/FAM65B pathway 39
BCL2 and miR-15/16: from gene discovery to treatment 38
SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition 37
MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake 36
Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation 36
Mutant p53 partners in crime 35
Deconstructing networks of p53-mediated tumor suppression in vivo 35
SREBP targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2 34
Relevance of the p53-MDM2 axis to aging 33
Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22 33
MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration 32
miRNA-21 ablation protects against liver injury and necroptosis in cholestasis 31
eIF2 alpha phosphorylation is pathognomonic for immunogenic cell death 31
Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture 30
Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation 30
KLF5 and MYC modulated LINC00346 contributes to gastric cancer progression through acting as a competing endogeous RNA and indicates poor outcome 26
Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models 26
An androgen receptor negatively induced long non-coding RNA ARNILA binding to miR-204 promotes the invasion and metastasis of triple-negative breast cancer 25
Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis 25
The lncRNA HOTAIR transcription is controlled by HNF4 alpha-induced chromatin topology modulation 25
Kynurenic acid, an IDO metabolite, controls TSG-6-mediated immunosuppression of human mesenchymal stem cells 24
New insights into apoptosome structure and function 24
Ferroptosis and necroinflammation, a yet poorly explored link 23
Crashing the computer: apoptosis vs. necroptosis in neuroinflammation 23
Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2 22
Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer 22
Necroptosis in anti-viral inflammation 22
p53 shades of Hippo 22