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SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammatio
Author: Sun, Yushuang; Xu, Shuqia; Wang, Dongyu; Gao, Shuiying; Qi, Xiaowen; Jiang, Miao; Jian, Dan; Li, Yaqiong; Jiang, Zhaoyan; Zhen, Miao; Wang, Peng; Shu, Bin; Xie, Julin; Chen, Demeng; Tang, Qing; Li, Jingting
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. 23, Issue 5, pp. 471-490. DOI: 10.1038/s41423-026-01410-1
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Acute stress alleviates type 2 lung inflammation by restricting ILC2s through corticosterone-glucocorticoid receptor signalin
Author: Zhu, Lin; Huang, Yuying; Peng, Bo; Zhong, Shufeng; Zhang, Xiaoyu; Xiao, Fuyang; Asim, Dilare; Pakezhati, Jieken; Ma, Jinquan; Sun, Siying; Xu, Jiefang; Cheng, Shipeng; Ma, Liyan; Ling, Zhiyang; Yi, Chuyan; Lu, Dongmei; Liang, Junqin; Sun, Bing
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. 23, Issue 5, pp. 546-559. DOI: 10.1038/s41423-026-01407-w
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Lipid metabolism reprogramming shapes the immune landscape in the tumor microenvironmen
Author: Du, Yun-Wei; Cai, Ze-Rong; Duan, Xiao-Tong; Li, Xin-Yu; Yue, Tong; Tian, Tian; Li, Jian-Jun; Ju, Huai-Qiang
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. 23, Issue 5, pp. 457-470. DOI: 10.1038/s41423-026-01411-0
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Hepatocyte-derived LRG1 primes the liver for metastasis and impairs immunotherap
Author: Long, Guojie; Cheng, Bing; Jiang, Yue; Liu, Qiufeng; Huang, Xiaoming; Niu, Zhitong; Xiao, Qian; Qian, Xiangjun; Wei, Chaoyin; Chen, Jinxin; Weng, Yingzhen; Zheng, Zheyu; Luo, Dandong; Ma, Tao; Su, Ting; Tang, Qiongwei; Wang, Panpan; Chen, Yufeng; Tan, Jing; Zhang, Ronghua; Yu, Qiang; Pan, Weidong; Wang, Wenyu
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. 23, Issue 5, pp. 560-574. DOI: 10.1038/s41423-026-01408-9
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MAIT cell plasticity generates CD4+ MAIT cells that promote HCC progression via metabolic crosstalk with tumor cell
Author: Fu, Sicheng; Tang, Maoyu; Zhao, Changfeng; Chen, Sanwei; Su, Miya; Pan, Jun; Zhang, Yuwei; Wang, Xiaohu; Jia, Wenhao; Chu, Xinmin; Chen, Shi; Chen, Yusheng; Chen, Lijian; Jin, Tengchuan; Tian, Zhigang; Sun, Yubei; Qian, Yeben; Liu, Lianxin; Wang, Hua; Zhang, Huimin; Bai, Li
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. 23, Issue 5, pp. 491-504. DOI: 10.1038/s41423-026-01409-8
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Interleukin enhancer binding factor 3 exacerbates cardiac inflammation and injury following myocardial infarction by inhibiting Lys48-linked ubiquitination on HNRNPA2B1 in macrophage
Author: Zhang, Xu; Wang, Peng; Liu, Long-hao; Zhang, Qiu-ting; Lv, Yuan-qing; Yang, Hong-rui; Hou, Ya-min; Li, Na; Cheng, Jie; Wang, Ze-ying; Wang, Ying; Zhao, Yuan-fei; Zhao, Zhi-wei; Zhang, Ming-xiang
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41423-026-01417-8
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B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8+ T-cell respons
Author: Liu, Xinyuan; Demircik, Filiz; Antipova, Mariia; Stylianakis, Emmanouil; Klein, Matthias; Bejarano, David; Elwy, Abdelrahman; Ebering, Anna; Blanfeld, Michaela; Carter, Katlynn; Johann, Lisa; Uhlfelder, David C.; Blickberndt, Elisa; Chen, Yao; Probst, Hans Christian; Hovelmeyer, Nadine; Bopp, Tobias; Arens, Ramon; Bunse, Lukas; Den Haan, Joke M. M.; Gommerman, Jennifer L.; Von Stebut, Esther; Clausen, Bjorn E.; Schlitzer, Andreas; Lang, Karl S.; Su, Bing; Backer, Ronald A.; Lemmermann, Niels A.; Waisman, Ari
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41423-026-01392-0
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Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killin
Author: Li, Xuemei; Schirra, Claudia; Wirkner, Marie-Louise; Tu, Szu-Min; Lin, Chin-Hsin; Hohmann, Meltem; Gu, Yuan; Santiago, Llipsy; Pardo, Julian; Arretxe, Inaki; Alawar, Nadia; Chouaib, Abed Alrahman; Becherer, Ute; Lee, Po-Hsien; Hsu, Hao-Jen; Laschke, Matthias W.; Baldari, Cosima T.; Dustin, Michael L.; Rettig, Jens; Krause, Elmar; Chang, Hsin-Fang
Journal: CELLULAR & MOLECULAR IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41423-026-01391-1
