Metabolic Engineering

Metabolic Engineering

代谢工程

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Pseudomonas putida as a functional chassis for industrial biocatalysis: From native biochemistry to trans-metabolism 61
Escherichia coli as a host for metabolic engineering 47
Recent advances in metabolic engineering of Saccharomyces cerevisiae: New tools and their applications 46
From lignin to nylon: Cascaded chemical and biochemical conversion using metabolically engineered Pseudomonas putida 42
Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene 40
The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology 35
Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production 33
Metabolic engineering of Escherichia coli for producing adipic acid through the reverse adipate-degradation pathway 31
Advances and prospects of Bacillus subtilis cellular factories: From rational design to industrial applications 27
Generation of a cluster-free Streptomyces albus chassis strains for improved heterologous expression of secondary metabolite clusters 27
Metabolic engineering of Pichia pastoris 26
Synthetic methanol auxotrophy of Escherichia coli for methanol-dependent growth and production 25
Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products 23
Metabolic engineering in the host Yarrowia lipolytica 23
Metabolic engineering of Pseudomonas taiwanensis VLB120 with minimal genomic modifications for high-yield phenol production 23
Engineering Corynebacterium glutamicum for methanol-dependent growth and glutamate production 22
MACBETH: Multiplex automated Corynebacterium glutamicum base editing method 22
Balancing the non-linear rosmarinic acid biosynthetic pathway by modular co-culture engineering 22
Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX 22
Coupling feedback genetic circuits with growth phenotype for dynamic population control and intelligent bioproduction 21
GC-MS-based C-13 metabolic flux analysis resolves the parallel and cyclic glucose metabolism of Pseudomonas putida KT2440 and Pseudomonas aeruginosa PAO1 21
Advances and prospects in metabolic engineering of Zymomonas mobilis 19
Tailored carbon partitioning for phototrophic production of (E)-alpha-bisabolene from the green microalga Chlamydomonas reinhardtii 19
Metabolic engineering of Escherichia coli for high-level astaxanthin production with high productivity 19
CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis 19
Model-assisted metabolic engineering of Escherichia coli for long chain alkane and alcohol production 18
Electrical-biological hybrid system for CO2 reduction 18
Boosting 11-oxo-ss-amyrin and glycyrrhetinic acid synthesis in Saccharomyces cerevisiae via pairing novel oxidation and reduction system from legume plants 18
Expression of heterologous non-oxidative pentose phosphate pathway from Bacillus methanolicus and phosphoglucose isomerase deletion improves methanol assimilation and metabolite production by a synthetic Escherichia coli methylotroph 18
Refactoring the upper sugar metabolism of Pseudomonas putida for co-utilization of cellobiose, xylose, and glucose 18
Streptomyces species: Ideal chassis for natural product discovery and overproduction 18
Systematically engineering the biosynthesis of a green biosurfactant surfactin by Bacillus subtilis 168 17
Enabling the valorization of guaiacol-based lignin: Integrated chemical and biochemical production of cis,cis-muconic acid using metabolically engineered Amycolatopsis sp ATCC 39116 17
Synthetic metabolic pathways for photobiological conversion of CO2 into hydrocarbon fuel 17
Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes 17
Temperature enhanced succinate production concurrent with increased central metabolism turnover in the cyanobacterium Synechocystis sp PCC 6803 17
Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica 17
Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica 17
Balancing cellular redox metabolism in microbial electrosynthesis and electro fermentation - A chance for metabolic engineering 16
RetroPath2.0: A retrosynthesis workflow for metabolic engineers 16
Rediverting carbon flux in Clostridium ljungdahlii using CRISPR interference (CRISPRi) 16
Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli 16
Engineering microbial membranes to increase stress tolerance of industrial strains 16
Engineered protein degradation of farnesyl pyrophosphate synthase is an effective regulatory mechanism to increase monoterpene production in Saccharomyces cerevisiae 15
Engineered monoculture and co-culture of methylotrophic yeast for de novo production of monacolin J and lovastatin from methanol 15
Photosynthesis-dependent biosynthesis of medium chain-length fatty acids and alcohols 15
Convergent engineering of syntrophic Escherichia coli coculture for efficient production of glycosides 15
CRISPR/Cas9 editing genome of extremophile Halomonas spp. 15
Heterologous transporter expression for improved fatty alcohol secretion in yeast 15
Methanol assimilation in Escherichia coli is improved by co-utilization of threonine and deletion of leucine-responsive regulatory protein 15