| Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases |
40 |
| Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes |
26 |
| Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives |
25 |
| Design, synthesis, molecular docking, and anticancer activity of benzoxazole derivatives as VEGFR-2 inhibitors |
24 |
| Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole |
21 |
| Recent updates of fluoroquinolones as antibacterial agents |
18 |
| meta-Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, -glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties |
16 |
| Synthesis and biological evaluation of phloroglucinol derivatives possessing -glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase inhibitory activity |
16 |
| Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7-dimethyl-5-oxo-8-tetrahydro-4H-chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials |
14 |
| Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors |
14 |
| Schiff bases and their amines: Synthesis and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors |
13 |
| Synthesis, characterization, and SAR of arylated indenoquinoline-based cholinesterase and carbonic anhydrase inhibitors |
10 |
| Some pyrazoles derivatives: Potent carbonic anhydrase, -glycosidase, and cholinesterase enzymes inhibitors |
10 |
| Antiparasitic activities of new lawsone Mannich bases |
9 |
| Therapeutic advancement of benzothiazole derivatives in the last decennial period |
9 |
| Novel sulfamate derivatives of menthol: Synthesis, characterization, and cholinesterases and carbonic anhydrase enzymes inhibition properties |
9 |
| Discovery and structure-activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells |
8 |
| Synthesis, molecular modeling, in vivo study, and anticancer activity of 4-triazole containing hydrazide-hydrazones derived from (S)-naproxen |
8 |
| Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties |
8 |
| Design, synthesis, in silico ADMET profile and GABA-A docking of novel phthalazines as potent anticonvulsants |
8 |
| Benzoxazole/benzothiazole-derived VEGFR-2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluations |
7 |
| Design, synthesis, and antitumor evaluation of quinoline-imidazole derivatives |
7 |
| Ursolic acid: Pharmacokinetics process in vitro and in vivo, a mini review |
7 |
| Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 4-thiazolidinedione derivatives as PPAR- modulators |
7 |
| Quinolone derivatives: Potential anti-HIV agent-development and application |
6 |
| Design, synthesis, and evaluation of anticonvulsant activities of benzoxazole derivatives containing the 4-triazolone moiety |
6 |
| New 4-disubstituted-2-thiopyrimidines as VEGFR-2 inhibitors: Design, synthesis, and biological evaluation |
6 |
| Synthesis, evaluation, and molecular docking studies of aryl urea-triazole-based derivatives as anti-urease agents |
6 |
| Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors |
6 |
| Design, synthesis, biological evaluation, and molecular modeling studies of rhodanine derivatives as pancreatic lipase inhibitors |
6 |
| Synthesis of novel sulfamides incorporating phenethylamines and determination of their inhibition profiles against some metabolic enzymes |
5 |
| Design, synthesis, and molecular docking of novel indole scaffold-based VEGFR-2 inhibitors as targeted anticancer agents |
5 |
| Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors |
5 |
| Synthesis and antimicrobial activity of novel 3-triazole-conjugates of quinazolin-4-ones |
5 |
| Synthesis, anticancer activity, and molecular modeling of etodolac-thioether derivatives as potent methionine aminopeptidase (type II) inhibitors |
5 |
| Synthesis, cytotoxic characterization, and SAR study of imidazo[2-b]pyrazole-7-carboxamides |
5 |
| Synthesis of beta-amino acid derivatives and their inhibitory profiles against some metabolic enzymes |
4 |
| Molecular insights into trypanothione reductase-inhibitor interaction: A structure-based review |
4 |
| Synthesis of substituted fluorobenzimidazoles as inhibitors of 5-lipoxygenase and soluble epoxide hydrolase for anti-inflammatory activity |
4 |
| Interconnection of sulfides and sulfoxides in medicinal chemistry |
4 |
| Gatifloxacin-3-triazole-isatin hybrids and their antimycobacterial activities |
4 |
| Quinoxaline and quinoxaline-4-di-N-oxides: An emerging class of antimycobacterials |
4 |
| Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation |
4 |
| Non-peptide-based new class of platelet aggregation inhibitors: Design, synthesis, bioevaluation, SAR, and in silico studies |
4 |
| Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors |
4 |
| Concise synthesis and antibacterial evaluation of novel 3-(4-disubstituted-3-triazolyl)uridine nucleosides |
4 |
| Quinazoline based 5-triazine derivatives as cancer inhibitors by impeding the phosphorylated RET tyrosine kinase pathway: Design, synthesis, docking, and QSAR study |
4 |
| Synthesis and anti-coronavirus activity of a series of 1-thia-4-azaspiro[4.5]decan-3-one derivatives |
4 |
| Design, synthesis, biological evaluation, and molecular dynamics of novel cholinesterase inhibitors as anti-Alzheimer's agents |
4 |
| Design, synthesis, and docking study of new quinoline derivatives as antitumor agents |
4 |
