Biochemical Pharmacology

Biochemical Pharmacology

生化药理学

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications 59
The P2X7 receptor: A main player in inflammation 41
Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization 40
Polyphenols, food and pharma. Current knowledge and directions for future research 34
A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator 34
The macrophage heme-heme oxygenase-1 system and its role in inflammation 34
A delicate balance - The BCL-2 family and its role in apoptosis, oncogenesis, and cancer therapeutics 32
Chondrocyte dedifferentiation and osteoarthritis (OA) 26
The therapeutic potential of purinergic signalling 26
Gasotransmitter hydrogen sulfide signaling in neuronal health and disease 26
The wonderland of neuronal nicotinic acetylcholine receptors 24
Canagliflozin exerts anti-inflammatory effects by inhibiting intracellular glucose metabolism and promoting autophagy in immune cells 24
H2S and polysulfide metabolism: Conventional and unconventional pathways 23
The many facets of macrophages in rheumatoid arthritis 23
Adipokines: Linking metabolic syndrome, the immune system, and arthritic diseases 23
Thrombospondin enhances RANKL-dependent osteoclastogenesis and facilitates lung cancer bone metastasis 22
Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway 22
Empagliflozin reduces the levels of CD36 and cardiotoxic lipids while improving autophagy in the hearts of Zucker diabetic fatty rats 22
Thrombospondin 2 promotes tumor metastasis by inducing matrix metalloproteinase-13 production in lung cancer cells 21
Osteoarthritis phenotypes and novel therapeutic targets 21
Human GIP(3-30)NH2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors 20
Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer 20
Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells 20
Aryl hydrocarbon receptor (AHR): From selected human target genes and crosstalk with transcription factors to multiple AHR functions 19
Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes 19
Alzheimer's disease (AD) therapeutics-1: Repeated clinical failures continue to question the amyloid hypothesis of AD and the current understanding of AD causality 19
Lung cancer stem cells: origin, features, maintenance mechanisms and therapeutic targeting 18
Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system 18
Autophagy inducers in cancer 17
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization 17
Resistin facilitates VEGF-C-associated lymphangiogenesis by inhibiting miR-186 in human chondrosarcoma cells 17
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide 17
Hydrogen sulfide in the regulation of insulin secretion and insulin sensitivity: Implications for the pathogenesis and treatment of diabetes mellitus 17
Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells 17
Targeting chronic innate inflammatory pathways, the main road to prevention of osteoarthritis progression 17
MicroRNA: A new generation therapeutic target in diabetic nephropathy 16
Nano-delivery systems for encapsulation of dietary polyphenols: An experimental approach for neurodegenerative diseases and brain tumors 16
Appraising the entourage effect: Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer 16
Ulixertinib (BVD-523) antagonizes ABCB1-and ABCG2-mediated chemotherapeutic drug resistance 16
Lanatoside C inhibits cell proliferation and induces apoptosis through attenuating Wnt/beta-catenin/c-Myc signaling pathway in human gastric cancer cell 16
Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells 16
Microglia-derived extracellular vesicles in Alzheimer's Disease: A double-edged sword 15
Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy 15
Cholinesterases and the fine line between poison and remedy 15
Monoacylglycerol lipase (MAGL) as a promising therapeutic target 15
Role of the endocannabinoid system in drug addiction 15
Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells 15
Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-kappa B/c-Myc pathway 15
Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation 15
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway 15