Phytomedicine

Phytomedicine

植物药

  • 1区 中科院分区
  • Q1 JCR分区

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Curcumin and quercetin synergistically inhibit cancer cell proliferation in multiple cancer cells and modulate Wnt/beta-catenin signaling and apoptotic pathways in A375 cells 28
In vivo effect of quantified flavonoids-enriched extract of Scutellaria baicalensis root on acute lung injury induced by influenza A virus 25
Natural products for the prevention and treatment of kidney disease 23
Gastroprotective effect of limonene in rats: Influence on oxidative stress, inflammation and gene expression 23
Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome 23
Cepharanthine: An update of its mode of action, pharmacological properties and medical applications 21
Effects of a new compound containing Palmitoylethanolamide and Baicalein in myocardial ischaemia/reperfusion injury in vivo 20
Identifying quality-markers from Shengmai San protects against transgenic mouse model of Alzheimer's disease using chinmedomics approach 20
Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway 20
Quercetin alleviates high glucose-induced damage on human umbilical vein endothelial cells by promoting autophagy 19
Luteolin protects against diabetic cardiomyopathy by inhibiting NF-kappa B-mediated inflammation and activating the Nrf2-mediated antioxidant responses 19
Apoptosis induced by luteolin in breast cancer: Mechanistic and therapeutic perspectives 19
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products 18
Tannins and vascular complications of Diabetes: An update 18
Rosmarinic acid attenuates development and existing pain in a rat model of neuropathic pain: An evidence of anti-oxidative and anti-inflammatory effects 17
Reversal effect of quercetin on multidrug resistance via FZD7/beta-catenin pathway in hepatocellular carcinoma cells 17
A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death 17
Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia 17
The natural phenolic compounds as modulators of NADPH oxidases in hypertension 17
Role of curcumin in the management of pathological pain 16
A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine 16
Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology 16
Fabrication of surfactant-stabilized nanosuspension of naringenin to surpass its poor physiochemical properties and low oral bioavailability 15
Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype 15
Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-beta-mediated Smad3 phosphorylation 15
Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway 15
Matrine induces apoptosis in multiple colorectal cancer cell lines in vitro and inhibits tumour growth with minimum side effects in vivo via Bcl-2 and caspase-3 15
Resveratrol mediated cancer cell apoptosis, and modulation of multidrug resistance proteins and metabolic enzymes 15
High-throughput chinmedomics strategy for discovering the quality-markers and potential targets for Yinchenhao decoction 14
Pentacyclic triterpenes: New tools to fight metabolic syndrome 14
Ligustilide attenuates vascular inflammation and activates Nrf2/HO-1 induction and, NO synthesis in HUVECs 13
Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials 13
Berberine down-regulates IL-8 expression through inhibition of the EGFR/MEK/ERK pathway in triple-negative breast cancer cells 13
Hydroxytyrosol NO regulates oxidative stress and NO production through SIRT1 in diabetic mice and vascular endothelial cells 13
Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis 13
Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells 13
Crocus sativus a natural food coloring and flavoring has potent anti-tumor properties 13
The effect of a garlic supplement on the pro-inflammatory adipocytokines, resistin and tumor necrosis factor-alpha, and on pain severity, in overweight or obese women with knee osteoarthritis 13
Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-kappa B/ERK signaling pathway in Raw264.7 cells 13
Anti-metastasis activity of curcumin against breast cancer via the inhibition of stem cell-like properties and EMT 13
Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats 13
Rhein protects the myocardiac cells against hypoxia/reoxygention-induced injury by suppressing GSK3 beta activity 13
Cinnamaldehyde and eugenol attenuates collagen induced arthritis via reduction of free radicals and pro-inflammatory cytokines 12
The antifibrotic and anti-inflammatory effects of icariin on the kidney in a unilateral ureteral obstruction mouse model 12
Flavonoids as Th1/Th2 cytokines immunomodulators: A systematic review of studies on animal models 12
Cytotoxicity of epunctanone and four other phytochemicals isolated from the medicinal plants Garcinia epunctata and Ptycholobium contortum towards multi-factorial drug resistant cancer cells 12
Salvianolate reduces atrial fibrillation through suppressing atrial interstitial fibrosis by inhibiting TGF-beta 1/Smad2/3 and TXNIP/NLRP3 inflammasome signaling pathways in post-MI rats 12
Allicin attenuates pathological cardiac hypertrophy by inhibiting autophagy via activation of PI3K/Akt/mTOR and MAPK/ERK/mTOR signaling pathways 12
Celastrol, a plant-derived triterpene, induces cisplatin-resistance nasopharyngeal carcinoma cancer cell apoptosis though ERK1/2 and p38 MAPK signaling pathway 12
Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy 12