Pharmacological Research

Pharmacological Research

药理研究

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Properties of FDA-approved small molecule protein kinase inhibitors 104
Small molecule inhibitors targeting the EGFR/ErbB family of protein-tyrosine kinases in human cancers 54
Hypertension and cardiovascular risk: General aspects 52
Astaxanthin: A mechanistic review on its biological activities and health benefits 49
Cyclin-dependent protein serine/threonine kinase inhibitors as anticancer drugs 49
Canonical and non-canonical mechanisms of Nrf2 activation 38
Gut microbiota, a new frontier to understand traditional Chinese medicines 34
A thermo-responsive alginate nanogel platform co-loaded with gold nanoparticles and cisplatin for combined cancer chemo-photothermal therapy 33
Targeting regulatory T cells by curcumin: A potential for cancer immunotherapy 33
Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy 31
Phytochemicals as inhibitors of NF-kappa B for treatment of Alzheimer's disease 31
Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway 30
Pharmacological targeting of RAS: Recent success with direct inhibitors 28
Targeting ERK1/2 protein-serine/threonine kinases in human cancers 27
Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms 27
Regulation of ER-mitochondria contacts by Parkin via Mfn2 26
Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies 26
Medicinal plants and bioactive natural compounds in the treatment of non-alcoholic fatty liver disease: A clinical review 26
Neurobiological links between depression and AD: The role of TGF-beta 1 signaling as a new pharmacological target 26
Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors 25
Therapeutic potential of curcumin in diabetic complications 25
Dioscin: A diverse acting natural compound with therapeutic potential in metabolic diseases, cancer, inflammation and infections 25
Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence 25
Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer's disease: A neuropharmacological review of their bioactive constituents 24
Nutraceuticals and functional foods for the control of plasma cholesterol levels. An intersociety position paper 24
Probiotics and antibiotic-associated diarrhea in children: A review and new evidence on Lactobacillus rhamnosus GG during and after antibiotic treatment 24
Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents 23
Possible use of Punica granatum (Pomegranate) in cancer therapy 23
Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets 22
Oral hydroxysafflor yellow A reduces obesity in mice by modulating the gut microbiota and serum metabolism 22
Understanding and overcoming the resistance of cancer to PD-1/PD-L1 blockade 22
Relevance of gutmicrobiota in cognition, behaviour and Alzheimer's disease 22
Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota 21
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway 21
Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and neurodegenerative diseases 21
A new dawn for managing dyslipidemias: The era of ma-based therapies 21
Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention 21
The clinical efficacy of curcumin-containing nutraceuticals: An overview of systematic reviews 20
Natural products targeting ER stress pathway for the treatment of cardiovascular diseases 20
Long noncoding RNAs act as regulators of autophagy in cancer 20
A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review 20
Potential role of genipin in cancer therapy 20
Targeting oncogenic Raf protein-serine/threonine kinases in human cancers 20
Tocotrienols: The promising analogues of vitamin E for cancer therapeutics 20
Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases 20
NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia 19
Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy 19
Beyond a neurotransmitter: The role of serotonin in inflammation and immunity 19
Pharmacokinetic drug interactions of the non-vitamin K antagonist oral anticoagulants (NOACs) 19
The beneficial roles of metformin on the brain with cerebral ischaemia/reperfusion injury 19