Drug Metabolism And Disposition

期刊发文

• Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum AlbuminS

  Author: Wu, Yali; Chen, Lili; Chen, Jian; Xue, Hao; He, Qingfeng; Zhong, Dafang; Diao, Xingxing

  Journal: DRUG METABOLISM AND DISPOSITION. 2023; Vol. 51, Issue 1, pp. 8-16. DOI: 10.1124/dmd.122.001019

• 50th Anniversary Celebration Collection Special Section on Xenobiotic Receptors The Function of Xenobiotic Receptors in Metabolic Diseases

  Author: Zhang, Jinhang; Jia, Qingyi; Li, Yanping; He, Jinhan

  Journal: DRUG METABOLISM AND DISPOSITION. 2023; Vol. 51, Issue 2, pp. 237-248. DOI: 10.1124/dmd.122.000862

• Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism[S]

  Author: Koubek, Emily J.; Buhrow, Sarah A.; Safgren, Stephanie L.; Jia, Lee; Goetz, Matthew P.; Ames, Matthew M.; Reid, Joel M.

  Journal: DRUG METABOLISM AND DISPOSITION. 2023; Vol. 51, Issue 2, pp. 183-192. DOI: 10.1124/dmd.122.000929

• Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor Profiles

  Author: Ekiciler, Aynur; Chen, Wen Li Kelly; Bo, Yan; Pugliano, Alessandra; Donzelli, Massimiliano; Parrott, Neil; Umehara, Kenichi

  Journal: DRUG METABOLISM AND DISPOSITION. 2023; Vol. 51, Issue 3, pp. 276-+. DOI: 10.1124/dmd.122.001132

• CYP3A4 and CYP3A5 Expression is Regulated by CYP3A4*1G in CRISPR/Cas9-Edited HepG2 Cells

  Author: Yang, Weihong; Zhao, Huan; Dou, Yaojie; Wang, Pei; Chang, Qi; Qiao, Xiaomeng; Wang, Xiaofei; Xu, Chen; Zhang, Zhe; Zhang, Lirong

  Journal: DRUG METABOLISM AND DISPOSITION. 2023; Vol. 51, Issue 4, pp. 492-498. DOI: 10.1124/dmd.122.001111

• Antibiotics-Induced Depletion of Rat Microbiota Induces Changes in the Expression of Host Drug-Processing Genes and Pharmacokinetic Behaviors of CYPs Probe DrugsS

  Author: Yang, Haijun; Zhang, Yanjuan; Zhou, Rong; Wu, Tianyuan; Zhu, Peng; Liu, Yujie; Zhou, Jian; Xiong, Yalan; Xiong, Yanling; Zhou, Honghao; Zhang, Wei; Shu, Yan; Li, Xiong; Li, Qing

  Journal: DRUG METABOLISM AND DISPOSITION. 2023; Vol. 51, Issue 4, pp. 509-520. DOI: 10.1124/dmd.122.001173

• Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation.

  Author: Tian Y¹, Cai J¹, Gui W¹, Nichols RG¹, Koo I¹, Zhang J¹, Anitha M¹, Patterson AD².

  Journal: Drug Metab Dispos. 2019 Feb;47(2):86-93. doi: 10.1124/dmd.118.083691. Epub 2018 Nov 8.

• Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases.

  Author: Kong F¹, Pang X¹, Zhao J¹, Deng P¹, Zheng M¹, Zhong D¹, Chen X².

  Journal: Drug Metab Dispos. 2019 Mar;47(3):238-248. doi: 10.1124/dmd.118.084640. Epub 2018 Dec 10.