| Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis |
32 |
| Global geographical and historical overview of cyanotoxin distribution and cyanobacterial poisonings |
31 |
| Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein |
29 |
| Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations |
26 |
| Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons |
26 |
| Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo |
24 |
| Management of oxidative stress and other pathologies in Alzheimer's disease |
24 |
| Nanomaterials: certain aspects of application, risk assessment and risk communication |
20 |
| Validation of the gamma H2AX biomarker for genotoxicity assessment: a review |
20 |
| Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures |
19 |
| Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid |
18 |
| The PPAR alpha-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions |
17 |
| Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells |
17 |
| 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo |
16 |
| Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins |
16 |
| Toxicity of blue led light and A2E is associated to mitochondrial dynamics impairment in ARPE-19 cells: implications for age-related macular degeneration |
16 |
| Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders |
15 |
| Emerging and established modes of cell death during acetaminophen-induced liver injury |
15 |
| Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes |
15 |
| In utero and lactational exposure to BDE-47 promotes obesity development in mouse offspring fed a high-fat diet: impaired lipid metabolism and intestinal dysbiosis |
14 |
| Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone |
13 |
| Gut microbiome disruption altered the biotransformation and liver toxicity of arsenic in mice |
13 |
| The protein corona suppresses the cytotoxic and pro-inflammatory response in lung epithelial cells and macrophages upon exposure to nanosilica |
13 |
| Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans |
13 |
| Alterations in epididymal proteomics and antioxidant activity of mice exposed to fluoride |
12 |
| The role of unfolded protein response and ER-phagy in quantum dots-induced nephrotoxicity: an in vitro and in vivo study |
12 |
| PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells |
12 |
| Intestinal toxicity of deoxynivalenol is limited by Lactobacillus rhamnosus RC007 in pig jejunum explants |
12 |
| The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells |
12 |
| Consequences of bisphenol a perinatal exposure on immune responses and gut barrier function in mice |
12 |
| Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells |
12 |
| Effects of cannabis tetrahydrocannabinol on endocannabinoid homeostasis in human placenta |
12 |
| Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells |
12 |
| In vitro-to-in vivo extrapolation (IVIVE) by PBTK modeling for animal-free risk assessment approaches of potential endocrine-disrupting compounds |
12 |
| Protective effect of cadmium-induced autophagy in rat renal mesangial cells |
11 |
| Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats |
11 |
| Urinary biomarkers of exposure to the mycoestrogen zearalenone and its modified forms in German adults |
11 |
| MicroRNAs in the diagnosis and prevention of drug-induced cardiotoxicity |
11 |
| Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay |
11 |
| Deepoxy-deoxynivalenol retains some immune-modulatory properties of the parent molecule deoxynivalenol in piglets |
11 |
| Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity |
11 |
| A systematic review of smoking-related epigenetic alterations |
11 |
| An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition |
11 |
| Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells |
11 |
| Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells |
11 |
| Head skeleton malformations in zebrafish (Danio rerio) to assess adverse effects of mixtures of compounds |
11 |
| Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1 alpha signaling |
11 |
| Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice |
10 |
| Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines |
10 |
| Hepatotoxic combination effects of three azole fungicides in a broad dose range |
10 |
