| Mechanistic targeting of advanced glycation end-products in age-related diseases |
27 |
| Endothelial cell senescence in aging-related vascular dysfunction |
27 |
| Klotho protects the heart from hyperglycemia-induced injury by inactivating ROS and NF-kappa B-mediated inflammation both in vitro and in vivo |
24 |
| Mitophagy and mitochondrial integrity in cardiac ischemia-reperfusion injury |
23 |
| TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway |
22 |
| Lipid droplet proteins and metabolic diseases |
21 |
| Melatonin protects diabetic heart against ischemia-reperfusion injury, role of membrane receptor-dependent cGMP-PKG activation |
21 |
| Functions and dysfunctions of nitric oxide in brain |
21 |
| Chemoresistance and chemosensitization in cholangiocarcinoma |
21 |
| Sirtuin 3-induced macrophage autophagy in regulating NLRP3 inflammasome activation |
20 |
| Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes |
19 |
| The role of xanthine oxidoreductase and uric acid in metabolic syndrome |
19 |
| Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy |
18 |
| The SGK1 inhibitor EMD63 prevents Angiotensin II-induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation |
18 |
| PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation |
18 |
| MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1 alpha |
18 |
| LncRNA UCA1 promotes migration and invasion in pancreatic cancer cells via the Hippo pathway |
17 |
| The GDF11-FTO-PPAR gamma axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis |
17 |
| Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca2+ handling |
17 |
| Novel MicroRNA-455-3p and its protective effects against abnormal APP processing and amyloid beta toxicity in Alzheimer's disease |
17 |
| BRG1 regulates endothelial-derived IL-33 to promote ischemia-reperfusion induced renal injury and fibrosis in mice |
17 |
| Metformin overcomes high glucose-induced insulin resistance of podocytes by pleiotropic effects on SIRT1 and AMPK |
17 |
| Bile acid receptors in the biliary tree: TGR5 in physiology and disease |
17 |
| GLP-1 receptor agonists and reduction of cardiometabolic risk: Potential underlying mechanisms |
16 |
| Mitochondrial fusion and maintenance of mitochondrial homeostasis in diabetic retinopathy |
16 |
| BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury |
16 |
| PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p |
15 |
| LncRNA TDRG1 enhances tumorigenicity in endometrial carcinoma by binding and targeting VEGF-A protein |
15 |
| Long non-coding RNA-ATB promotes EMT during silica-induced pulmonary fibrosis by competitively binding miR-200c |
15 |
| Farnesoid X receptor: A homeostat for hepatic nutrient metabolism |
15 |
| Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy |
15 |
| Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration |
14 |
| Animal models to study bile acid metabolism |
14 |
| PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis |
14 |
| Brg1 regulates pro-lipogenic transcription by modulating SREBP activity in hepatocytes |
14 |
| Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling |
14 |
| Type 2 diabetes - An autoinflammatory disease driven by metabolic stress |
14 |
| Drosophila as a model for ageing |
14 |
| Non-human primates as a model for aging |
14 |
| The role of mitochondria in sepsis-induced cardiomyopathy |
14 |
| Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: Protection by Melatonin |
13 |
| Fibroblast growth factor 21 protects the heart from angiotensin II-induced cardiac hypertrophy and dysfunction via SIRT1 |
13 |
| Hydrogen sulfide attenuates oxidative stress-induced NLRP3 inflammasome activation via S-sulfhydrating c-Jun at Cys269 in macrophages |
13 |
| Aging across the tree of life: The importance of a comparative perspective for the use of animal models in aging |
13 |
| Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production |
13 |
| The chromatin remodeling protein BRG1 regulates APAP-induced liver injury by modulating CYP3A11 transcription in hepatocyte |
13 |
| The role of NADPH oxidases in diabetic cardiomyopathy |
13 |
| Molecular mechanisms of cardiac pathology in diabetes - Experimental insights |
13 |
| Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling |
13 |
| Inhibition of canonical WNT signaling pathway by beta-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12 |
13 |
