| Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing |
28 |
| Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway |
25 |
| Metformin as a geroprotector: experimental and clinical evidence |
19 |
| Gene expression hallmarks of cellular ageing |
15 |
| Age-related changes in skeletal muscle: changes to life-style as a therapy |
15 |
| Telomere and its role in the aging pathways: telomere shortening, cell senescence and mitochondria dysfunction |
13 |
| D-Galactose-induced accelerated aging model: an overview |
13 |
| The receptor for advanced glycation end-products (RAGE) is an important pattern recognition receptor (PRR) for inflammaging |
12 |
| Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence |
10 |
| Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decreaseDNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts |
9 |
| Peroxisomes: role in cellular ageing and age related disorders |
8 |
| Echinacoside, a phenylethanoid glycoside from Cistanche deserticola, extends lifespan of Caenorhabditis elegans and protects from A beta-induced toxicity |
7 |
| The mTORC1-autophagy pathway is a target for senescent cell elimination |
7 |
| Oxidative stress resistance as a factor in aging: evidence from an extended longevity phenotype of Drosophila melanogaster |
7 |
| N-Acetylcysteine extends lifespan of Drosophila via modulating ROS scavenger gene expression |
7 |
| Involvement of the autophagic pathway in the progression of AMD-like retinopathy in senescence-accelerated OXYS rats |
6 |
| Long-term exposure to TNF-alpha leads human skin fibroblasts to a p38 MAPK- and ROS-mediated premature senescence |
6 |
| Organ reserve, excess metabolic capacity, and aging |
6 |
| Mitochondrial dysfunction in metabolism and ageing: shared mechanisms and outcomes? |
6 |
| Reversing the immune ageing clock: lifestyle modifications and pharmacological interventions |
5 |
| The impact of aging on CD4(+) T cell responses to influenza infection |
5 |
| Polyphenols protect against age-associated apoptosis in female rat cochleae |
5 |
| Repurposed FDA-approved drugs targeting genes influencing aging can extend lifespan and healthspan in rotifers |
5 |
| Some naturally occurring compounds that increase longevity and stress resistance in model organisms of aging |
5 |
| Larval crowding results in hormesis-like effects on longevity in Drosophila: timing of eclosion as a model |
5 |
| Late-onset administration of GDF11 extends life span and delays development of age-related markers in the annual fish Nothobranchius guentheri |
5 |
| Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases |
5 |
| Age-related loss of VGLUT1 excitatory, but not VGAT inhibitory, immunoreactive terminals on motor neurons in spinal cords of old sarcopenic male mice |
5 |
| Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions |
5 |
| Rates of erythropoiesis in mammals and their relationship with lifespan and hematopoietic stem cells aging |
4 |
| Influence of aging on germinal centre reaction and antibody response to inactivated influenza virus antigens in mice: sex-based differences |
4 |
| A network-based meta-analysis for characterizing the genetic landscape of human aging |
4 |
| Mitochondria, its DNA and telomeres in ageing and human population |
4 |
| Can markers of biological age predict dependency in old age? |
4 |
| Short-term dietary restriction in old mice rejuvenates the aging-induced structural imbalance of gut microbiota |
4 |
| Carbohydrate-restricted diet promotes skin senescence in senescence-accelerated prone mice |
4 |
| Amino acids and amino acid sensing: implication for aging and diseases |
4 |
| Caloric restriction improves the redox homeostasis in the aging male rat heart even when started in middle-adulthood and when the body weight is stable |
4 |
| Development, lifespan and reproduction of spider mites exposed to predator-induced stress across generations |
3 |
| Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways |
3 |
| l-Carnitine inhibits the senescence-associated secretory phenotype of aging adipose tissue by JNK/p53 pathway |
3 |
| Circadian clock genes' overexpression in Drosophila alters diet impact on lifespan |
3 |
| The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood |
3 |
| Genetic background, epigenetic factors and dietary interventions which influence human longevity |
3 |
| Limited daily feeding and intermittent feeding have different effects on regional brain energy homeostasis during aging |
3 |
| The protective function of non-coding DNA in DNA damage accumulation with age and its roles in age-related diseases |
3 |
| Mitigating peroxynitrite mediated mitochondrial dysfunction in aged rat brain by mitochondria-targeted antioxidant MitoQ |
3 |
| Elevated levels of the small GTPase Cdc42 induces senescence in male rat mesenchymal stem cells |
3 |
| A review of telomere length in sarcopenia and frailty |
3 |
| Accumulation of glycated proteins suggesting premature ageing in lamin B receptor deficient mice |
3 |
