Cancer Gene Therapy

Cancer Gene Therapy

癌症基因治疗

  • 3区 中科院分区
  • Q1 JCR分区

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LncRNA-SNHG16 predicts poor prognosis and promotes tumor proliferation through epigenetically silencing p21 in bladder cancer 25
LncRNA SNHG14 promotes inflammatory response induced by cerebral ischemia/reperfusion injury through regulating miR-136-5p/ROCK1 23
miR-200c inhibits TGF-beta-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer 18
miR-140-5p inhibits the proliferation and enhances the efficacy of doxorubicin to breast cancer stem cells by targeting Wnt1 15
Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System (R) (RTS (R)) gene switch as gene therapy for the treatment of glioma 15
Long non-coding RNA DLEU1 predicts poor prognosis of gastric cancer and contributes to cell proliferation by epigenetically suppressing KLF2 14
Serum exosomes contain ECRG4 mRNA that suppresses tumor growth via inhibition of genes involved in inflammation, cell proliferation, and angiogenesis 14
Inhibition of microRNA-384-5p alleviates osteoarthritis through its effects on inhibiting apoptosis of cartilage cells via the NF-kappa B signaling pathway by targeting SOX9 13
Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy 11
CRISPR/Cas9 genome editing technology significantly accelerated herpes simplex virus research 11
Genomic landscape and prognostic analysis of mantle cell lymphoma 11
c-Myc induced upregulation of long non-coding RNA SNHG16 enhances progression and carcinogenesis in oral squamous cell carcinoma 10
Dissecting the functional role of microRNA 21 in osteosarcoma 10
Let-7b attenuates cisplatin resistance and tumor growth in gastric cancer by targeting AURKB 9
Enhanced expressions of FHL2 and iASPP predict poor prognosis in acute myeloid leukemia 9
JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models 9
Upregulating microRNA-498 inhibits gastric cancer proliferation invasion and chemoresistance through inverse interaction of Bmi1 8
Development of an adenovirus vector vaccine platform for targeting dendritic cells 8
Arming oncolytic reovirus with GM-CSF gene to enhance immunity 8
Prognostic role of DOK family adapters in acute myeloid leukemia 8
T-bet promotes potent antitumor activity of CD4(+) CAR T cells 8
Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference 7
miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells 7
MicroRNA21 and the various types of myeloid leukemia 6
MicroRNA-122 negatively associates with peroxiredoxin-II expression in human gefitinib-resistant lung cancer stem cells 6
GINS2 promotes cell proliferation and inhibits cell apoptosis in thyroid cancer by regulating CITED2 and LOXL2 5
Inhibitor of growth 3 induces cell death by regulating cell proliferation, apoptosis and cell cycle arrest by blocking the PI3K/AKT pathway 5
Upregulation of microRNA-3129 suppresses epithelial ovarian cancer through CD44 5
Netrin-1 elicits metastatic potential of non-small cell lung carcinoma cell by enhancing cell invasion, migration and vasculogenic mimicry via EMT induction 5
LncRNA SPRY4-IT was concerned with the poor prognosis and contributed to the progression of thyroid cancer 5
Quantification and functional evaluation of CD40L production from the adenovirus vector ONCOS-401 5
ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway 5
Intratumoral IFN-alpha gene delivery reduces tumor-infiltrating regulatory T cells through the downregulation of tumor CCL17 expression 5
High expression of UBE2T predicts poor prognosis and survival in multiple myeloma 5
Down-regulated long non-coding RNA RNAZFHX4-AS1 suppresses invasion and migration of breast cancer cells via FAT4-dependent Hippo signaling pathway 5
Complex consisting of antisense DNA and beta-glucan promotes internalization into cell through Dectin-1 and hybridizes with target mRNA in cytosol 4
Gene therapy for castration-resistant prostate cancer cells using JC polyomavirus-like particles packaged with a PSA promoter driven-suicide gene 4
Clinical and biological implications of mutational spectrum in acute myeloid leukemia of FAB subtypes M4 and M5 4
Gene expression profiles reveal key genes for early diagnosis and treatment of adamantinomatous craniopharyngioma 4
High expression levels of SMAD3 and SMAD7 at diagnosis predict poor prognosis in acute myeloid leukemia patients undergoing chemotherapy 3
Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer 3
Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA combined with cisplatin inhibits cellular growth and induces apoptosis in HPV-positive head and neck cancer cells 3
Silencing SATB1 overcomes temozolomide resistance by downregulating MGMT expression and upregulating SLC22A18 expression in human glioblastoma cells 3
Downregulation of miR-152 contributes to DNMT1-mediated silencing of SOCS3/SHP-1 in non-Hodgkin lymphoma 3
Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer 3
Endostatin gene therapy delivered by attenuated Salmonella typhimurium in murine tumor models 3
Clinical characteristics and prognostic analysis of multiple primary malignant neoplasms in patients with lung cancer 2
Efficient tumor transduction and antitumor efficacy in experimental human osteosarcoma using retroviral replicating vectors 2
Schwannoma gene therapy by adeno-associated virus delivery of the pore-forming protein Gasdermin-D 2
Synergistic antitumour effects of rapamycin and oncolytic reovirus 2