Cancer Immunology Immunotherapy

Cancer Immunology Immunotherapy

癌症免疫学免疫治疗

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions 43
TIGIT: a novel immunotherapy target moving from bench to bedside 42
Quantifying tumor-infiltrating immune cells from transcriptomics data 40
Immune cell infiltration as a biomarker for the diagnosis and prognosis of stage I-III colon cancer 33
The correlation and prognostic value of serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death-ligand 1 (sPD-L1) in patients with hepatocellular carcinoma 30
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates 28
Post-treatment neutrophil-to-lymphocyte ratio at week 6 is prognostic in patients with advanced non-small cell lung cancers treated with anti-PD-1 antibody 28
The binding of an anti-PD-1 antibody to Fc gamma RI has a profound impact on its biological functions 27
Ipilimumab in metastatic melanoma patients with pre-existing autoimmune disorders 25
Opposing roles of eosinophils in cancer 23
The class I/IV HDAC inhibitor mocetinostat increases tumor antigen presentation, decreases immune suppressive cell types and augments checkpoint inhibitor therapy 22
Targeting myeloid-derived suppressor cells for cancer immunotherapy 22
Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models 22
Transcriptomic analysis of the tumor microenvironment to guide prognosis and immunotherapies 20
Immunotherapy with checkpoint inhibitors in non-small cell lung cancer: insights from long-term survivors 20
Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapy 20
Regulatory mechanisms of PD-L1 expression in cancer cells 20
Organ-specific response to nivolumab in patients with non-small cell lung cancer (NSCLC) 19
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression 19
Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model 19
Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2 18
Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells 18
Pretreatment neutrophil-to-lymphocyte ratio is associated with outcome of advanced-stage cancer patients treated with immunotherapy: a meta-analysis 18
Targeting tumor-associated acidity in cancer immunotherapy 17
Characterization of arthralgia induced by PD-1 antibody treatment in patients with metastasized cutaneous malignancies 17
Induction of a central memory and stem cell memory phenotype in functionally active CD4(+) and CD8(+) CAR T cells produced in an automated good manufacturing practice system for the treatment of CD19(+) acute lymphoblastic leukemia 17
Indoleamine 3-dioxygenase provides adaptive resistance to immune checkpoint inhibitors in hepatocellular carcinoma 17
A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer 17
Modulation of NK cells with checkpoint inhibitors in the context of cancer immunotherapy 17
Cross-talk between TNF-alpha and IFN-gamma signaling in induction of B7-H1 expression in hepatocellular carcinoma cells 16
Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report 16
High PDL1 mRNA expression predicts better survival of stage pT1 non-muscle-invasive bladder cancer (NMIBC) patients 16
Monitoring of patients with metastatic melanoma treated with immune checkpoint inhibitors using PET-CT 16
Pre-existing autoimmune disease and the risk of immune-related adverse events among patients receiving checkpoint inhibitors for cancer 16
VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival 15
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient 15
IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients 15
How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions 15
Bile duct obstruction in a patient treated with nivolumab as second-line chemotherapy for advanced non-small-cell lung cancer: a case report 15
The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer 15
Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC 15
Characterization of circulating T NK and NKT cell subsets in patients with colorectal cancer: the peripheral blood immune cell profile 14
Expression of the inhibitory B7 family molecule VISTA in human colorectal carcinoma tumors 14
Increased antitumor activities of glypican-3-specific chimeric antigen receptor-modified T cells by coexpression of a soluble PD1-CH3 fusion protein 14
Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism 14
First-line therapy-stratified survival in BRAF-mutant melanoma: a retrospective multicenter analysis 14
Fighting breast cancer stem cells through the immune-targeting of the xCT cystine-glutamate antiporter 13
Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies 13
mTOR-mediated glycolysis contributes to the enhanced suppressive function of murine tumor-infiltrating monocytic myeloid-derived suppressor cells 13
Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation 13