Clinical Cancer Research

Clinical Cancer Research

临床癌症研究

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
FDA Approval Summary: Pembrolizumab for the Treatment of Microsatellite Instability-High Solid Tumors 113
Oxidative Phosphorylation as an Emerging Target in Cancer Therapy 106
WNT/beta-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers 87
Clinical Significance of PD-L1(+) Exosomes in Plasma of Head and Neck Cancer Patients 78
Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade 77
PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial-Mesenchymal Transition 70
Anti-PD-1 Antibody SHR-1210 Combined with Apatinib for Advanced Hepatocellular Carcinoma, Gastric, or Esophagogastric Junction Cancer: An Open-label, Dose Escalation and Expansion Study 67
Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non-small Cell Lung Cancer 66
Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers 65
Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes 65
CAR T Cells Targeting B7-H a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors 64
Deep Learning-Based Multi-Omics Integration Robustly Predicts Survival in Liver Cancer 63
The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients 63
False-Positive Plasma Genotyping Due to Clonal Hematopoiesis 62
T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma 61
Investigating Novel Resistance Mechanisms to Third-Generation EGFR Tyrosine Kinase Inhibitor Osimertinib in Non-Small Cell Lung Cancer Patients 60
Breast Cancer Immunotherapy: Facts and Hopes 57
Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers 57
Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies 57
Phase I Trial of M7824 (MSB0011359C), a Bifunctional Fusion Protein Targeting PD-L1 and TGF beta, in Advanced Solid Tumors 56
Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA 54
Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis 53
The Role of Angiogenesis in Hepatocellular Carcinoma 52
Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial 51
Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC 51
Long Noncoding RNA LINC01234 Functions as a Competing Endogenous RNA to Regulate CBFB Expression by Sponging miR-204-5p in Gastric Cancer 51
Validation of a Plasma-Based Comprehensive Cancer Genotyping Assay Utilizing Orthogonal Tissue- and Plasma-Based Methodologies 51
Residual Convolutional Neural Network for the Determination of IDH Status in Low- and High-Grade Gliomas from MR Imaging 51
High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden 51
Long Noncoding RNA NEAT Regulated by the EGFR Pathway, Contributes to Glioblastoma Progression Through the WNT/beta-Catenin Pathway by Scaffolding EZH2 48
Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab 47
Safety and Antitumor Activity of Pembrolizumab in Patients with Estrogen Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer 47
Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging 47
Age Correlates with Response to Anti-PD Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations 46
The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 807 Advanced Cancer Patients 46
Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1-Based Immunotherapy 45
FDA Approval Summary: (Daunorubicin and Cytarabine) Liposome for Injection for the Treatment of Adults with High-Risk Acute Myeloid Leukemia 45
Antibody-Drug Conjugates: Future Directions in Clinical and Translational Strategies to Improve the Therapeutic Index 45
TP STK and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti-PD-1 in Lung Adenocarcinoma 44
LncRNA-FEZFl-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling 44
Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations 44
Prognostic Significance of Tumor-Infiltrating B Cells and Plasma Cells in Human Cancer 44
Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3(+) Regulatory T Cells (Tregs) in Human Cancers 43
DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies 43
Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer 43
Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention 43
Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2 thorn Breast Cancer Metastasis to the Brain 43
Radiomics of Multiparametric MRI for Pretreatment Prediction of Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study 42
Focal Irradiation and Systemic TGF beta Blockade in Metastatic Breast Cancer 42
CD103(+) Tumor-Resident CD8(+) T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment 41