Current Opinion In Chemical Biology

Current Opinion In Chemical Biology

化学生物学的当前观点

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Targeted protein degradation: elements of PROTAC design 65
Fundamentals of ion mobility spectrometry 39
Getting to know the neighborhood: using proximity-dependent biotinylation to characterize protein complexes and map organelles 38
Anticancer metal-N-heterocyclic carbene complexes of gold, platinum and palladium 33
Inhibitors of protein-protein interactions (PPIs): an analysis of scaffold choices and buried surface area 33
Collision induced unfolding of isolated proteins in the gas phase: past, present, and future 28
The roles of microRNAs in epigenetic regulation 27
Carboxylic acid reductase enzymes (CARs) 26
Transaminases for chiral amine synthesis 26
Synthesis of chiral amines using redox biocatalysis 25
Chemical cross-linking with mass spectrometry: a tool for systems structural biology 24
Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics 24
Natural product derived privileged scaffolds in drug discovery 24
The application of ion-mobility mass spectrometry for structure/function investigation of protein complexes 24
Trending topics and open questions in anaerobic ammonium oxidation 23
Selective C-H bond functionalization with engineered heme proteins: new tools to generate complexity 23
Protein identification strategies in MALDI imaging mass spectrometry: a brief review 22
Insights into the physiology of ammonia-oxidizing microorganisms 22
The potential of ion mobility-mass spectrometry for non-targeted metabolomics 21
Recent advances in DNA nanotechnology 21
Reactive sulfur species (RSS): persulfides, polysulfides, potential, and problems 20
Biocatalytic reduction of activated C=C-bonds and beyond: emerging trends 19
Bifunctional chemical probes inducing protein-protein interactions 19
Reactive-cysteine profiling for drug discovery 19
Will morphing boron-based inhibitors beat the beta-lactamases? 19
Recent preparative applications of redox enzymes 18
'Democratized' genomic enzymology web tools for functional assignment 18
Recent developments in the application of P450 based biocatalysts 18
The potential of Ion Mobility Mass Spectrometry for high-throughput and high-resolution lipidomics 17
Next-generation genetic code expansion 17
Metal complexes promoting catalytic cleavage of nucleic acids - biochemical tools and therapeutics 17
Activity-based sensing fluorescent probes for iron in biological systems 17
Advances in mass spectrometry imaging coupled to ion mobility spectrometry for enhanced imaging of biological tissues 17
Shedding light on biocatalysis: photoelectrochemical platforms for solar-driven biotransformation 17
An overview of activity-based probes for glycosidases 16
Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo 16
The application of ion mobility mass spectrometry to metabolomics 16
Recent advances in the optical control of protein function through genetic code expansion 16
Targeted protein degradation and the enzymology of degraders 15
Whole-cell based synthetic enzyme cascades-light and shadow of a promising technology 15
New players in phototherapy: photopharmacology and bio-integrated optoelectronics 15
A bright future: optogenetics to dissect the spatiotemporal control of cell behavior 15
DNA methylation as a genomic marker of exposure to chemical and environmental agents 14
Image scanning microscopy 14
Aptamer-based and aptazyme-based riboswitches in mammalian cells 14
Recent progress in photoacoustic molecular imaging 14
Synthesis of modified proteins dehydroalanine 14
Creation of unnatural base pairs for genetic alphabet expansion toward synthetic xenobiology 14
Advancing the large-scale CCS database for metabolomics and lipidomics at the machine-learning era 13
Probing microscopic conformational dynamics in folding reactions by measuring transition paths 13