| Targeting the renin-angiotensin system as novel therapeutic strategy for pulmonary diseases |
42 |
| The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases |
37 |
| Stem cell-based therapeutic strategies for cartilage defects and osteoarthritis |
28 |
| Musculoskeletal senescence: a moving target ready to be eliminated |
20 |
| Mechanisms of resistance in estrogen receptor positive breast cancer: overcoming resistance to tamoxifen/aromatase inhibitors |
20 |
| Monoclonal antibodies as immunomodulatory therapy against cancer and autoimmune diseases |
19 |
| Mechanisms and therapeutic targets for bone damage in rheumatoid arthritis, in particular the RANK-RANKL system |
17 |
| Flavonoids in hypertension: a brief review of the underlying mechanisms |
17 |
| Targeting WNT signaling in the treatment of osteoporosis |
15 |
| Recent advances in combinatorial drug screening and synergy scoring |
15 |
| Peptides as cancer vaccines |
15 |
| mGlu receptors in the treatment of Parkinson's disease and L-DOPA-induced dyskinesia |
14 |
| The antimalarial pipeline |
13 |
| Angiogenesis in peripheral arterial disease |
13 |
| New developments in the treatment of gastroparesis and functional dyspepsia |
13 |
| Evolution of fecal microbiota transplantation in methodology and ethical issues |
13 |
| Targeting immune checkpoints in non small cell lung cancer |
12 |
| Role of the P2X4 receptor in neuropathic pain |
12 |
| New and emerging anti-fibrotic therapeutics entering or already in clinical trials in chronic liver diseases |
12 |
| Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment |
12 |
| Enteroviral infections in the pathogenesis of type 1 diabetes: new insights for therapeutic intervention |
12 |
| Pre- and probiotic overview |
12 |
| Trained immunity as a novel therapeutic strategy |
11 |
| The present state of the tuberculosis drug development pipeline |
11 |
| The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis |
11 |
| Improving therapy of severe infections through drug repurposing of synergistic combinations |
11 |
| Heterogeneity and emergent behaviour in the vascular endothelium |
11 |
| Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis |
10 |
| Novel biologics targeting the P2X7 ion channel |
10 |
| Adjuvant strategies to improve vaccination of the elderly population |
10 |
| Autophagy pathways in the treatment of prion diseases |
10 |
| Mechanisms of artemisinin resistance in Plasmodium falciparum malaria |
10 |
| Role of the P2X7 receptor in tumor-associated inflammation |
9 |
| Pharmacological mechanisms leading to synergy in fixed-dose dual bronchodilator therapy |
9 |
| Targeting arginase and nitric oxide metabolism in chronic airway diseases and their co-morbidities |
9 |
| Combination and inducible adjuvants targeting nucleic acid sensors |
9 |
| Mucosal IgE immune responses in respiratory diseases |
9 |
| State of the art and pharmacological pipeline of biologics for chronic plaque psoriasis |
9 |
| Mucosal permeability and mast cells as targets for functional gastrointestinal disorders |
9 |
| The cholinergic anti-inflammatory pathway: an innovative treatment strategy for respiratory diseases and their comorbidities |
9 |
| Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics |
9 |
| Intra-articular drug delivery systems for joint diseases |
9 |
| Gene therapy for repair and regeneration of bone and cartilage |
9 |
| Tumor targeting peptides: novel therapeutic strategies in glioblastoma |
8 |
| The future of peptides in cancer treatment |
8 |
| The therapeutic potential of metabotropic glutamate receptor modulation for schizophrenia |
8 |
| Immunomodulatory effects of P2X7 receptor in intracellular parasite infections |
8 |
| Bioactive cell penetrating peptides and proteins in cancer: a bright future ahead |
8 |
| Pharmacological development in hidradenitis suppurativa |
8 |
| Cell therapy for peripheral artery disease |
8 |
