Current Topics In Medicinal Chemistry

Current Topics In Medicinal Chemistry

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高引用文章

文章名称 引用次数
Coumarin Compounds in Medicinal Chemistry: Some Important Examples from the Last Years 28
Recent Development of Small Molecule Glutaminase Inhibitors 24
Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer 23
Bis-coumarin Derivatives and their Biological Activities 18
Molecular Hybridization as a Tool for Designing Multitarget Drug Candidates for Complex Diseases 18
Advancements in Docking and Molecular Dynamics Simulations Towards Ligand-receptor Interactions and Structure -function Relationships 18
SCAP/SREBPs are Central Players in Lipid Metabolism and Novel Meta-bolic Targets in Cancer Therapy 18
Target Enzyme in Alzheimer's Disease: Acetylcholinesterase Inhibitors 15
MicroRNAs as Therapeutic Agents: The Future of the Battle Against Cancer 14
Small-Molecule Immuno-Oncology Therapy: Advances, Challenges and New Directions 14
Overcoming the Psychiatric Side Effects of the Cannabinoid CB1 Receptor Antagonists: Current Approaches for Therapeutics Development 13
Emerging Complexity and the Need for Advanced Drug Delivery in Targeting Candida Species 13
An Update on MDMX and Dual MDM2/X Inhibitors 12
Toward Small-molecule Inhibition of Protein-protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions 12
Impacts of Pseudo Amino Acid Components and 5-steps Rule to Proteomics and Proteome Analysis 11
Giardiasis: Characteristics, Pathogenesis and New Insights About Treatment 11
Structure-Based Drug Design Strategies and Challenges 11
Conventional Versus Natural Alternative Treatments for Leishmaniasis: A Review 10
From Receptor Selectivity to Functional Selectivity: The Rise of Biased Agonism in 5-HT1A Receptor Drug Discovery 10
Biological Activities of Artemisinin Derivatives Beyond Malaria 9
Nanoparticle Therapy for Prostate Cancer: Overview and Perspectives 9
The Mechanism of Action of Praziquantel: Six Hypotheses 9
Internet Resources for Drug Discovery and Design 9
Quantum Molecular Dynamics, Topological, Group Theoretical and Graph Theoretical Studies of Protein-Protein Interactions 9
STAT3: A Potential Drug Target for Tumor and Inflammation 9
Network Pharmacology: Exploring the Resources and Methodologies 9
New Benzothiazole-based Thiazolidinones as Potent Antimicrobial Agents. Design, Synthesis and Biological Evaluation 9
Depression Assessment in Clinical Trials and Pre-clinical Tests: A Critical Review 9
Anxiety Disorders: Sex Differences in Serotonin and Tryptophan Metabolism 9
PTP1b Inhibition, A Promising Approach for the Treatment of Diabetes Type II 8
Leishmaniasis and Chagas Disease - Neglected Tropical Diseases: Treatment Updates 8
Virtual Screening Techniques in Drug Discovery: Review and Recent Applications 8
Mycobacterial tuberculosis Enzyme Targets and their Inhibitors 8
Small Molecule Natural Products and Alzheimer's Disease 8
Searching for New Targets and Treatments in the Battle Against Squamous Cell Carcinoma of the Head and Neck, with Specific Focus on Tumours of the Tongue 8
DNA Methyltransferase Inhibitors and their Therapeutic Potential 8
Histone Deacetylase Inhibitors in Cancer Therapy 8
Epigenetic Targets and their Inhibitors in Cancer Therapy 8
Structure-based Methods for Binding Mode and Binding Affinity Prediction for Peptide-MHC Complexes 7
Inhibition of Pyruvate Dehydrogenase Kinase as a Therapeutic Strategy against Cancer 7
Targeting Key Transporters in Tumor Glycolysis as a Novel Anticancer Strategy 7
Peptide Sequence-Dominated Enzyme-Responsive Nanoplatform for Anticancer Drug Delivery 7
An Overview on the Potential Antimycobacterial Agents Targeting Serine/Threonine Protein Kinases from Mycobacterium tuberculosis 7
Mathematical and Computational Techniques for Drug Discovery: Promises and Developments 7
Design, Synthesis, Evaluation of Antimicrobial Activity and Docking Studies of New Thiazole-based Chalcones 7
Chemistry and Biology of Farnesol and its Derivatives: Quorum Sensing Molecules with Immense Therapeutic Potential 7
Protease Inhibitors for the Treatment of HIV/AIDS: Recent Advances and Future Challenges 7
Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication 7
Structure-Based Virtual Screening for the Identification of High Affinity Compounds as Potent VEGFR2 Inhibitors for the Treatment of Renal Cell Carcinoma 7
Recent Development of Coumarin Derivatives as Potential Antiplasmodial and Antimalarial Agents 7