Embo Journal

Embo Journal

恩博杂志

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Past, present, and future of circRNAs 101
Tau protein liquid-liquid phase separation can initiate tau aggregation 92
Long-term expanding human airway organoids for disease modeling 80
Microglial subtypes: diversity within the microglial community 57
Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1 56
p62 filaments capture and present ubiquitinated cargos for autophagy 53
Length-independent telomere damage drives post-mitotic cardiomyocyte senescence 51
The complex relationship between TFEB transcription factor phosphorylation and subcellular localization 49
Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis 47
Collided ribosomes form a unique structural interface to induce Hel2-driven quality controlpathways 46
Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly 44
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival 44
Phase separation of 53BP1 determines liquid-like behavior of DNA repair compartments 44
Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent 42
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing 39
Xenograft and organoid model systems in cancer research 37
The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes 35
Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery 35
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase 34
Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo 33
Mechanism of membrane pore formation by human gasdermin-D 33
Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution 33
Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis 32
Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments 32
Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death 31
A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex 31
Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy 30
Extracellular matrix sensing by FERONIA and Leucine-Rich Repeat Extensins controls vacuolar expansion during cellular elongation in Arabidopsis thaliana 30
Systemic inflammation impairs microglial A beta clearance through NLRP3 inflammasome 30
The assembly of lipid droplets and their roles in challenged cells 29
LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation 29
Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria 28
Plant photoreceptors and their signaling components compete for COP1 binding via VP peptide motifs 27
A single-cell transcriptome atlas of the adult human retina 27
PIF4-induced BR synthesis is critical to diurnal and thermomorphogenic growth 27
3D model for CAR-mediated cytotoxicity using patient-derived colorectal cancer organoids 25
LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation 25
RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation 24
Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency 24
SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice 24
ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport 24
DNA damage kinase signaling: checkpoint and repair at 30 years 23
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy 23
OST1-mediated BTF3L phosphorylation positively regulates CBFs during plant cold responses 23
Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis 22
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages 22
Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis 22
Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting 21
NF-kappa B activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS 21
Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3 20