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The latest investigational drugs for patients with allergic rhiniti
Author: Fang, Dandan; Zhang, Yuan; Zhang, Luo
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2026; Vol. , Issue , pp. -. DOI: 10.1080/13543784.2025.2612328
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Safety, pharmacokinetics, and efficacy of HY-072808 ointment, a novel PDE4 inhibitor, in adolescent and adult patients with mild-to-moderate A
Author: Yao, Feng; He, Mingchao; Wang, Jing; Li, Yao; Zhang, Qian; Yang, Jingjing; Wu, Jingying; Zhang, Qin; Zhou, Renpeng; Zhang, Meiling; Meng, Linying; Wu, Liming; Chu, Zhaoxing; Hu, Wei
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2025; Vol. 34, Issue 5, pp. 435-447. DOI: 10.1080/13543784.2025.2510671
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Safety, tolerability, pharmacokinetics, and pharmacodynamics of SHR-2010, a novel anti-MASP-2 antibody, in healthy volunteers: a randomized, double-blind, placebo-controlled phase 1 stud
Author: Lin, Pingping; Wang, Chenjing; Hu, Xiaotong; Fang, Lin; Lin, Hongda; Sun, Feifei; Huang, Rong; Ban, Rongxin; Feng, Sheng; Gao, Zhenyan; Shen, Kai; Cao, Yu
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2025; Vol. 34, Issue 4, pp. 339-348. DOI: 10.1080/13543784.2025.2500291
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A phase 1, randomized, double-blind, placebo-controlled trial investigating the safety, tolerability, pharmacokinetics, and pharmacodynamics of KN056 (a recombinant human GLP-1 variant Fc fusion protein) in healthy Chinese participant
Author: Qin, Yuan-Fang; Zhang, Wen-Hua; Zhang, Hao-Nan; Li, Yu-Wei; Huang, Wen-Qiao; Xie, Jin-Lian; Yang, Shuang; Li, Lan-Ni; Cui, Chang; Pei, Qi; Huang, Jie; Yang, Guo-Ping
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2025; Vol. 34, Issue 4, pp. 329-337. DOI: 10.1080/13543784.2025.2500303
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Evaluation of pharmacokinetic and pharmacodynamic similarity of an IDegAsp biosimilar versus the originator in healthy Chinese volunteer
Author: Liu, Hui; Xiong, Yang; Chen, Xinlei; Yu, Hongling; Lan, Li; He, Wengang; Wang, Wenjia; Zhuang, Yulei; Deng, Li; Huang, Kanghua; Guo, Linfeng; Yu, Yerong
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2025; Vol. 34, Issue 1-2, pp. 97-104. DOI: 10.1080/13543784.2025.2463085
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First-in-human study on tolerability, pharmacokinetics and pharmacodynamics of single and multiple escalating doses of XKH001, a recombinant humanized monoclonal antibody against IL-25 in healthy Chinese volunteer
Author: Zhang, Hong; Zheng, Wenbo; Peng, Ran; Wu, Dandan; Hu, Yue; Sun, Tiantian; Gao, Lei; Liu, Yusi; Guo, Li; Ding, Yanhua; Liu, Li
Journal: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2025; Vol. , Issue , pp. -. DOI: 10.1080/13543784.2025.2453162
