| Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC |
74 |
| Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice |
55 |
| Long noncoding RNA SNHG1 promotes non-small cell lung cancer progression by up-regulating MTDH via sponging miR-145-5p |
41 |
| AMPK in skeletal muscle function and metabolism |
38 |
| Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy |
38 |
| Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons |
31 |
| Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes |
26 |
| Exosome-associated miRNA profile as a prognostic tool for therapy response monitoring in multiple sclerosis patients |
25 |
| Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment |
24 |
| Tissue-specific regulation of cytochrome c by post-translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis |
24 |
| ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori |
24 |
| Endothelial microRNAs regulating the NF-kappa B pathway and cell adhesion molecules during inflammation |
23 |
| The glymphatic mechanism for solute clearance in Alzheimer's disease: game changer or unproven speculation? |
23 |
| Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate rat hepatic ischemia-reperfusion injury by suppressing oxidative stress and neutrophil inflammatory response |
23 |
| Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging |
22 |
| Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease |
21 |
| FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis |
21 |
| Lack of acute xenogeneic graft-versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression |
21 |
| Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer |
20 |
| The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy |
19 |
| Activation of ROS/MAPKs/NF-kappa B/NLRP3 and inhibition of efferocytosis in osteoclast-mediated diabetic osteoporosis |
19 |
| NEAT1 is overexpressed in Parkinson's disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress |
19 |
| Skeletal cell YAP and TAZ combinatorially promote bone development |
19 |
| Melanin distribution in human epidermis affords localized protection against DNA photodamage and concurs with skin cancer incidence difference in extreme phototypes |
19 |
| METTL3 inhibits BMSC adipogenic differentiation by targeting the JAK1/STAT5/C/EBP beta pathway via an m(6)A-YTHDF2-dependent manner |
19 |
| Maternal choline supplementation during the third trimester of pregnancy improves infant information processing speed: a randomized, double-blind, controlled feeding study |
18 |
| Extracellular RNAs in periodontopathogenic outer membrane vesicles promote TNF-alpha production in human macrophages and cross the blood-brain barrier in mice |
18 |
| Zinc reduces hepatic lipid deposition and activates lipophagy via Zn2+/MTF-1/PPAR and Ca2+/CaMKK/AMPK pathways |
18 |
| Maintained exercise-enhanced brain executive function related to cerebral lactate metabolism in men |
18 |
| IKK2/NF-kappa B signaling protects neurons after traumatic brain injury |
18 |
| Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death |
18 |
| Omega-3 fatty acid supplementation attenuates skeletal muscle disuse atrophy during two weeks of unilateral leg immobilization in healthy young women |
17 |
| Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw |
17 |
| Timing of food intake impacts daily rhythms of human salivary microbiota: a randomized, crossover study |
16 |
| Primary endothelial cell-specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia |
16 |
| miR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma |
16 |
| MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytes |
16 |
| Exercise training during chemotherapy preserves skeletal muscle fiber area, capillarization, and mitochondrial content in patients with breast cancer |
16 |
| IL-17 induces cellular stress microenvironment of melanocytes to promote autophagic cell apoptosis in vitiligo |
15 |
| Poor expression of microRNA-135b results in the inhibition of cisplatin resistance and proliferation and induces the apoptosis of gastric cancer cells through MST1-mediated MAPK signaling pathway |
15 |
| Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy |
15 |
| Identification of novel proteolytically inactive mutations in coronavirus 3C-like protease using a combined approach |
15 |
| MicroRNA-124 regulates the expression of p62/p38 and promotes autophagy in the inflammatory pathogenesis of Parkinson's disease |
15 |
| Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome |
15 |
| Gut microbiome catabolites as novel modulators of muscle cell glucose metabolism |
15 |
| SIRT1 antagonizes liver fibrosis by blocking hepatic stellate cell activation in mice |
15 |
| BMSCs protect against renal ischemia-reperfusion injury by secreting exosomes loaded with miR-199a-5p that target BIP to inhibit endoplasmic reticulum stress at the very early reperfusion stages |
15 |
| Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia |
15 |
| Exosomes in postshock mesenteric lymph are key mediators of acute lung injury triggering the macrophage activation via Toll-like receptor 4 |
15 |
| Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity |
14 |
