| Roles of the immune system in cancer: from tumor initiation to metastatic progression |
157 |
| Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m(6)A machinery component Wtap/Fl(2)d |
56 |
| Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences |
54 |
| Necroptosis in development and diseases |
49 |
| Regulation of lipid peroxidation and ferroptosis in diverse species |
46 |
| Phase separation of Polycomb-repressive complex 1 is governed by a charged disordered region of CBX2 |
45 |
| A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs |
39 |
| MITF-the first 25 years |
39 |
| Role of tumor and host autophagy in cancer metabolism |
37 |
| Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation |
35 |
| Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer |
34 |
| Genetics and biology of prostate cancer |
34 |
| Widespread transcriptional pausing and elongation control at enhancers |
32 |
| The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription |
31 |
| Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program |
31 |
| CD44 splice isoform switching determines breast cancer stem cell state |
31 |
| POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer |
30 |
| Bridging barriers: a comparative look at the blood-brain barrier across organisms |
28 |
| Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts |
28 |
| PRC2 is high maintenance |
27 |
| Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation |
26 |
| Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling |
24 |
| The impact of mitotic errors on cell proliferation and tumorigenesis |
24 |
| Transcription-mediated replication hindrance: a major driver of genome instability |
24 |
| Host-transposon interactions: conflict, cooperation, and cooption |
24 |
| MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer |
23 |
| ZNF445 is a primary regulator of genomic imprinting |
22 |
| Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer |
22 |
| A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease |
21 |
| Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52 |
21 |
| Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1 alpha |
21 |
| Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities |
20 |
| Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells |
20 |
| High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brain |
19 |
| RNA m(6)A modification enzymes shape innate responses to DNA by regulating interferon beta |
19 |
| RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening |
19 |
| Helix-loop-helix proteins and the advent of cellular diversity: 30 years of discovery |
18 |
| ZCCHC the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation |
18 |
| The Integrator complex cleaves nascent mRNAs to attenuate transcription |
18 |
| The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation |
17 |
| Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity |
17 |
| The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action |
17 |
| WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks |
16 |
| A novel DCL2-dependent miRNA pathway in tomato affects susceptibility to RNA viruses |
15 |
| lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures |
15 |
| Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming |
15 |
| Stem cell niche-specific Ebf3 maintains the bone marrow cavity |
15 |
| Auxin: a molecular trigger of seed development |
15 |
| Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells |
15 |
| Programming for T-lymphocyte fates: modularity and mechanisms |
15 |
