| Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis |
38 |
| PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality (18)fluorine-2-fluoro-2-deoxy-D-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer |
19 |
| Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study |
19 |
| The UK EndoVascular Aneurysm Repair (EVAR) randomised controlled trials: long-term follow-up and cost-effectiveness analysis |
18 |
| Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation |
14 |
| AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies |
12 |
| Low-dose computed tomography for lung cancer screening in high-risk populations: a systematic review and economic evaluation |
11 |
| What works to increase attendance for diabetic retinopathy screening? An evidence synthesis and economic analysis |
11 |
| Selective laser trabeculoplasty versus drops for newly diagnosed ocular hypertension and glaucoma: the LiGHT RCT |
9 |
| Treatments for dry age-related macular degeneration and Stargardt disease: a systematic review |
8 |
| A randomised controlled trial and economic evaluation of intraoperative cell salvage during caesarean section in women at risk of haemorrhage: the SALVO (cell SALVage in Obstetrics) trial |
8 |
| Improving the Quality of Dentistry (IQuaD): a cluster factorial randomised controlled trial comparing the effectiveness and cost-benefit of oral hygiene advice and/or periodontal instrumentation with routine care for the prevention and management of periodontal disease in dentate adults attending dental primary care |
8 |
| Self-Management education for adults with poorly controlled epILEpsy [SMILE (UK)]: a randomised controlled trial |
7 |
| E-cigarettes compared with nicotine replacement therapy within the UK Stop Smoking Services: the TEC RCT |
7 |
| Structured lifestyle education to support weight loss for people with schizophrenia, schizoaffective disorder and first episode psychosis: the STEPWISE RCT |
7 |
| Everolimus, lutetium-177 DOTATATE and sunitinib for advanced, unresectable or metastatic neuroendocrine tumours with disease progression: a systematic review and cost-effectiveness analysis |
7 |
| Ten-year follow-up of a randomised trial of drainage, irrigation and fibrinolytic therapy (DRIFT) in infants with post-haemorrhagic ventricular dilatation |
7 |
| Anal fistula plug versus surgeon's preference for surgery for trans-sphincteric anal fistula: the FIAT RCT |
7 |
| Interventions to improve the mental health of children and young people with long-term physical conditions: linked evidence syntheses |
7 |
| Goal-oriented cognitive rehabilitation for early-stage Alzheimer's and related dementias: the GREAT RCT |
6 |
| The 4 'A's test for detecting delirium in acute medical patients: a diagnostic accuracy study |
6 |
| 3-month versus 6-month adjuvant chemotherapy for patients with high-risk stage II and III colorectal cancer: 3-year follow-up of the SCOT non-inferiority RCT |
6 |
| Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation |
6 |
| Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT |
6 |
| Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM) Introduction |
6 |
| Early, specialist vocational rehabilitation to facilitate return to work after traumatic brain injury: the FRESH feasibility RCT |
6 |
| Negative-pressure wound therapy versus standard dressings for adults with an open lower limb fracture: the WOLLF RCT |
6 |
| MRI in the diagnosis of fetal developmental brain abnormalities: the MERIDIAN diagnostic accuracy study |
6 |
| Metformin in non-diabetic hyperglycaemia: the GLINT feasibility RCT |
6 |
| Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis |
5 |
| Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis |
5 |
| Gastrostomy versus nasogastric tube feeding for chemoradiation patients with head and neck cancer: the TUBE pilot RCT |
5 |
| Combining optical coherence tomography with visual field data to rapidly detect disease progression in glaucoma: a diagnostic accuracy study |
5 |
| Lamotrigine for people with borderline personality disorder: a RCT |
5 |
| Positive behaviour support training for staff for treating challenging behaviour in people with intellectual disabilities: a cluster RCT |
5 |
| Amaze: a double-blind, multicentre randomised controlled trial to investigate the clinical effectiveness and cost-effectiveness of adding an ablation device-based maze procedure as an adjunct to routine cardiac surgery for patients with pre-existing atrial fibrillation |
4 |
| A pedometer-based walking intervention in 45-to 75-year-olds, with and without practice nurse support: the PACE-UP three-arm cluster RCT |
4 |
| Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT |
4 |
| The West Midlands ActiVe lifestyle and healthy Eating in School children (WAVES) study: a cluster randomised controlled trial testing the clinical effectiveness and cost-effectiveness of a multifaceted obesity prevention intervention programme targeted at children aged 6-7 years |
4 |
| Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation |
4 |
| High-throughput non-invasive prenatal testing for fetal rhesus D status in RhD-negative women not known to be sensitised to the RhD antigen: a systematic review and economic evaluation |
4 |
| Cabozantinib and vandetanib for unresectable locally advanced or metastatic medullary thyroid cancer: a systematic review and economic model |
4 |
| The feasibility of early pulmonary rehabilitation and activity after COPD exacerbations: external pilot randomised controlled trial, qualitative case study and exploratory economic evaluation |
4 |
| Therapist telephone-delivered CBT and web-based CBT compared with treatment as usual in refractory irritable bowel syndrome: the ACTIB three-arm RCT |
4 |
| Manualised cognitive-behavioural therapy in treating depression in advanced cancer: the CanTalk RCT |
4 |
| The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling |
4 |
| Brain and spinal stimulation therapies for phantom limb pain: a systematic review |
4 |
| Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT |
4 |
| Multiple-frequency bioimpedance devices for fluid management in people with chronic kidney disease receiving dialysis: a systematic review and economic evaluation |
4 |
| Exercise- and strategy-based physiotherapy-delivered intervention for preventing repeat falls in people with Parkinson's: the PDSAFE RCT |
4 |
