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Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer's disease
Author: Zhang, Changjun; Zhang, Yujia; Lv, Yangjing; Guo, Jianan; Gao, Bianbian; Lu, Yi; Zang, Anjie; Zhu, Xi; Zhou, Tao; Xie, Yuanyuan
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. 100-117. DOI: 10.1080/14756366.2022.2134358
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Binding selectivity-dependent molecular mechanism of inhibitors towards CDK2 and CDK6 investigated by multiple short molecular dynamics and free energy landscapes
Author: Wang, Lifei; Lu, Dan; Wang, Yan; Xu, Xiaoyan; Zhong, Peihua; Yang, Zhiyong
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. 84-99. DOI: 10.1080/14756366.2022.2135511
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Development of 10-Hydroxycamptothecin-crizotinib conjugate based on the synergistic effect on lung cancer cells
Author: Liu, Zhen; Xu, Ye; Guo, Lvqian; Li, Xinran; Gao, Junling; Xie, Weiran; Zhao, Lianbo; Teng, Yuou; Li, Xuejiao; Yu, Peng
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. 1-11. DOI: 10.1080/14756366.2022.2132487
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Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity
Author: Fu, Dong-Jun; Wang, Ting
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. 166-175. DOI: 10.1080/14756366.2022.2136173
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Design, synthesis and biological evaluation of 4-aminoquinoline derivatives as receptor-interacting protein kinase 2 (RIPK2) inhibitors
Author: Fan, Tiantian; Ji, Yinchun; Chen, Danqi; Peng, Xia; Ai, Jing; Xiong, Bing
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. 282-293. DOI: 10.1080/14756366.2022.2148317
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Ligand-based discovery of coronavirus main protease inhibitors using MACAW molecular embeddings
Author: Dong, Jie; Varbanov, Mihayl; Philippot, Stephanie; Vreken, Fanny; Zeng, Wen-Bin; Blay, Vincent
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. 24-35. DOI: 10.1080/14756366.2022.2132486
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Bioactivity and mechanisms of flavonoids in decreasing insulin resistance
Author: Zhou, Min; Konigsberg, William H.; Hao, Canhua; Pan, Yinbo; Sun, Jie; Wang, Xiaojing
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. -. DOI: 10.1080/14756366.2023.2199168
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Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells
Author: Zhang, Guanglong; Tang, Zhenhua; Fan, Sili; Li, Chengpeng; Li, Yan; Liu, Weiqin; Long, Xuesha; Zhang, Wenjing; Zhang, Yi; Li, Zhurui; Wang, Zhenchao; Chen, Danping; Ouyang, Guiping
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2023; Vol. 38, Issue 1, pp. -. DOI: 10.1080/14756366.2022.2163393
