Journal Of Experimental & Clinical Cancer Research

Journal Of Experimental & Clinical Cancer Research

实验与临床癌症研究杂志

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Combination of CTLA-4 and PD-1 blockers for treatment of cancer 80
Advances in cancer immunotherapy 2019-latest trends 72
Notch1 signaling in melanoma cells promoted tumor-induced immunosuppression via upregulation of TGF-beta 1 66
STAT3 as a potential therapeutic target in triple negative breast cancer: a systematic review 61
Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis 60
Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype 57
LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling 56
Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis 56
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway 54
CircRNA circRNA_102171 promotes papillary thyroid cancer progression through modulating CTNNBIP1-dependent activation of -catenin pathway 50
MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer 49
Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology 48
CircSETD3 (Hsa_circ_0000567) acts as a sponge for microRNA-421 inhibiting hepatocellular carcinoma growth 47
RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer 46
Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA 42
New therapeutic strategies to treat human cancers expressing mutant p53 proteins 42
SP1-induced lncRNA AGAP2-AS1 expression promotes chemoresistance of breast cancer by epigenetic regulation of MyD88 41
Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts 41
Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway 41
Circular RNA hsa_circ_0068871 regulates FGFR3 expression and activates STAT3 by targeting miR-181a-5p to promote bladder cancer progression 40
Role of metabolism in cancer cell radioresistance and radiosensitization methods 40
Cancer DNA vaccines: current preclinical and clinical developments and future perspectives 40
circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346 37
circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma 36
Classification of triple-negative breast cancers based on Immunogenomic profiling 36
FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma 36
The role of cellular reactive oxygen species in cancer chemotherapy 35
ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway 34
SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2/LSD1/DNMT1 and sponging miR-101-3p in cholangiocarcinoma 33
HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3 33
Macrophage-derived exosomal microRNA-501-3p promotes progression of pancreatic ductal adenocarcinoma through the TGFBR3-mediated TGF-beta signaling pathway 33
Clinical development of targeted and immune based anti-cancer therapies 33
Long non-coding RNA GAS5 inhibits DDP-resistance and tumor progression of epithelial ovarian cancer via GAS5-E2F4-PARP1-MAPK axis 32
Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways 32
Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia 31
Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma 31
Long non-coding RNA AGAP2-AS functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma 31
LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells 31
Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 gene in glioblastoma multiforme 31
Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis regulates breast cancer stemness via Wnt/beta-catenin pathway 31
Exosomal miR-9 inhibits angiogenesis by targeting MDK and regulating PDK/AKT pathway in nasopharyngeal carcinoma 30
The roles of glucose metabolic reprogramming in chemo- and radio-resistance 30
MiR-9 promotes tumorigenesis and angiogenesis and is activated by MYC and OCT4 in human glioma 30
Targeting KRAS in metastatic colorectal cancer: current strategies and emerging opportunities 29
Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway 29
Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression 29
HIF-2 alpha promotes conversion to a stem cell phenotype and induces chemoresistance in breast cancer cells by activating Wnt and Notch pathways 29
Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling 29
Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells 28
From bench to bed: the tumor immune microenvironment and current immunotherapeutic strategies for hepatocellular carcinoma 28