Journal Of General Physiology

Journal Of General Physiology

普通生理学杂志

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Structure, function, and allosteric modulation of NMDA receptors 44
Revisiting multimodal activation and channel properties of Pannexin 1 17
Structural mechanisms of CFTR function and dysfunction 16
KCNMA1-linked channelopathy 14
The relationship between form and function throughout the history of excitation-contraction coupling 14
Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis 13
Known structures and unknown mechanisms of TMEM16 scramblases and channels 13
Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel 12
The ins and outs of vesicular monoamine transporters 11
Cryo-electron microscopy structures and progress toward a dynamic understanding of K-ATP channels 11
Calcium-induced release of calcium in muscle: 50 years of work and the emerging consensus 11
The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis 10
A perspective on Na and K channel inactivation 10
Molecular determination of claudin-15 organization and channel selectivity 10
Structural insights into the mechanisms of CNBD channel function 9
Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors 9
Identifying the molecular target sites for CFTR potentiators GLPG1837 and VX-770 9
A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine 9
Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors 9
The hERG potassium channel intrinsic ligand regulates N- and C-terminal interactions and channel closure 9
Conduction through a narrow inward-rectifier K+ channel pore 9
Physiological CRAC channel activation and pore properties require STIM1 binding to all six Orai1 subunits 8
Voltage-clamp recordings of light responses from wild-type and mutant mouse cone photoreceptors 8
SR Ca2+ leak in skeletal muscle fibers acts as an intracellular signal to increase fatigue resistance 8
Nitroxyl (HNO) targets phospholamban cysteines 41 and 46 to enhance cardiac function 8
Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete beta-adrenergic response 8
Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance 7
A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel 7
ATP is stored in lamellar bodies to activate vesicular P2X(4) in an autocrine fashion upon exocytosis 7
The weak voltage dependence of pannexin 1 channels can be tuned by N-terminal modifications 7
Electrical coupling and its channels 7
Tetrodotoxin-sensitive Na(v)s contribute to early and delayed afterdepolarizations in long QT arrhythmia models 6
The contribution of voltage clamp fluorometry to the understanding of channel and transporter mechanisms 6
Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition 6
Mitochondrial ATP synthase dimers spontaneously associate due to a long-range membrane-induced force 6
The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening 6
The lipid bilayer membrane and its protein constituents 6
The discovery of the ability of rod photoreceptors to signal single photons 6
Unraveling the mechanisms of calcium-dependent secretion 6
A stochastic model of ion channel cluster formation in the plasma membrane 6
Outer hair cell electromotility is low-pass filtered relative to the molecular conformational changes that produce nonlinear capacitance 6
Gating currents 6
Differential contribution of Ca2+ sources to day and night BK current activation in the circadian clock 6
It takes two to tango: The dance of the permease 6
Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity 5
TREK-1 channels regulate pressure sensitivity and calcium signaling in trabecular meshwork cells 5
Different agonists induce distinct single-channel conductance states in TRPV1 channels 5
Coupling between an electrostatic network and the Zn2+ binding site modulates Hv1 activation 5
Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers 5
Evolution of our understanding of cell volume regulation by the pump-leak mechanism 5