Medicinal Research Reviews

Medicinal Research Reviews

医学研究评论

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one 62
Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era 50
Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs 45
Health benefits of resveratrol: Evidence from clinical studies 45
Biologically active quinoline and quinazoline alkaloids part I 42
Small molecule inhibitors of mammalian thioredoxin reductase as potential anticancer agents: An update 34
Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment 34
Recent clinical trends in Toll-like receptor targeting therapeutics 32
Comprehensive review of cardiovascular toxicity of drugs and related agents 30
JNK signaling in cancer cell survival 28
Strategies to diversify natural products for drug discovery 28
Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancer 27
The multifaceted role of autophagy in cancer and the microenvironment 26
Immunomodulators targeting the PD-1/PD-L1 protein-protein interaction: From antibodies to small molecules 25
The Current State of NAD(+)-Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets 24
A(3) Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 24
Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review 23
Dimethyl fumarate, a two-edged drug: Current status and future directions 23
Recent progress in the antiviral activity and mechanism study of pentacyclic triterpenoids and their derivatives 22
Chitosan-based multifunctional nanomedicines and theranostics for targeted therapy of cancer 21
Targeting EGFR(L858R/T790M) and EGFR(L858R/T790M/C797S) resistance mutations in NSCLC: Current developments in medicinal chemistry 20
Selective targeting of antiapoptotic BCL-2 proteins in cancer 20
Proteases and protease inhibitors in infectious diseases 20
Biologically active quinoline and quinazoline alkaloids part II 19
Hypoxia-inducible factor-1 (HIF-1) inhibitors from the last decade (2007 to 2016): A structure-activity relationship perspective 19
Complex roles of the old drug aspirin in cancer chemoprevention and therapy 19
Targeting prostate cancer: Prostate-specific membrane antigen based diagnosis and therapy 19
Development of Safe Drugs: The hERG Challenge 19
Atheroprotective Effects and Molecular Targets of Tanshinones Derived From Herbal Medicine Danshen 19
Efflux pump inhibitors of clinically relevant multidrug resistant bacteria 19
Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study 18
Therapeutic strategies involving survivin inhibition in cancer 18
Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives 18
Chemical modifications of nucleic acid drugs and their delivery systems for gene-based therapy 17
The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role 17
Intramolecular hydrogen bonding: An opportunity for improved design in medicinal chemistry 17
Progress and challenges in the prevention and control of nonalcoholic fatty liver disease 17
Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues 17
Free Fatty Acid Receptor 1 (FFAR1) as an Emerging Therapeutic Target for Type 2 Diabetes Mellitus: Recent Progress and Prevailing Challenges 17
Antiaging effects of bioactive molecules isolated from plants and fungi 15
Strategies to target the Hedgehog signaling pathway for cancer therapy 14
Monoamine oxidase-B inhibitors as potential neurotherapeutic agents: An overview and update 13
Antibacterial and beta-Lactamase Inhibitory Activity of Monocyclic beta-Lactams 13
Emerging roles of allosteric modulators in the regulation of protein-protein interactions (PPIs): A new paradigm for PPI drug discovery 13
Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases 12
Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic target 12
Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research-practice gaps, challenges, and insights 12
Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive Potential 12
Carbohydrate-based vaccines for oncotherapy 11
Lipidic prodrug approach for improved oral drug delivery and therapy 11