| The NLRP3 inflammasome: molecular activation and regulation to therapeutics |
315 |
| NF-kappa B, inflammation, immunity and cancer: coming of age |
289 |
| Neutrophil extracellular traps in immunity and disease |
209 |
| Microglia and macrophages in brain homeostasis and disease |
171 |
| The diverse functions of the PD1 inhibitory pathway |
163 |
| Macrophages as regulators of tumour immunity and immunotherapy |
145 |
| CD4(+) T cell help in cancer immunology and immunotherapy |
139 |
| Towards personalized, tumour-specific, therapeutic vaccines for cancer |
129 |
| Single-cell RNA sequencing to explore immune cell heterogeneity |
126 |
| Natural killer cells and other innate lymphoid cells in cancer |
108 |
| Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer |
104 |
| Dendritic cell subsets in T cell programming: location dictates function |
99 |
| The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease |
99 |
| Defining 'T cell exhaustion' |
90 |
| Type 2 immunity in tissue repair and fibrosis |
86 |
| Integrating oncolytic viruses in combination cancer immunotherapy |
75 |
| Immune checkpoint blockade in infectious diseases |
68 |
| C-type lectins in immunity and homeostasis |
68 |
| Cardioimmunology: the immune system in cardiac homeostasis and disease |
67 |
| Beyond binding: antibody effector functions in infectious diseases |
65 |
| IFN gamma: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy |
63 |
| Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight |
61 |
| The hygiene hypothesis in autoimmunity: the role of pathogens and commensals |
59 |
| The tumour glyco-code as a novel immune checkpoint for immunotherapy |
58 |
| Heterogeneity of neutrophils |
57 |
| Clocking in to immunity |
57 |
| The spectrum of T cell metabolism in health and disease |
55 |
| Regulatory mechanisms in T cell receptor signalling |
54 |
| The human antibody response to influenza A virus infection and vaccination |
54 |
| The immunological anatomy of the skin |
52 |
| Osteoimmunology: evolving concepts in bone-immune interactions in health and disease |
51 |
| HLA variation and disease |
50 |
| Autophagy in the renewal, differentiation and homeostasis of immune cells |
49 |
| Small RNA-based antimicrobial immunity |
48 |
| Complement in cancer: untangling an intricate relationship |
48 |
| Mining the microbiota for microbial and metabolite-based immunotherapies |
47 |
| Itaconate: the poster child of metabolic reprogramming in macrophage function |
47 |
| Improving immune-vascular crosstalk for cancer immunotherapy |
47 |
| Passive immunotherapy of viral infections: 'super-antibodies' enter the fray |
46 |
| Calcium signalling in T cells |
45 |
| Targeting cytokines to treat asthma and chronic obstructive pulmonary disease |
45 |
| Immunometabolism at the interface between macrophages and pathogens |
44 |
| Immune mechanisms of hypertension |
42 |
| Epigenetic control of CD8(+) T cell differentiation |
41 |
| Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity? |
41 |
| Targeting innate immune mediators in type 1 and type 2 diabetes |
41 |
| T(H)2 cell development and function |
40 |
| Immunometabolism and natural killer cell responses |
37 |
| Epigenetic regulation of the innate immune response to infection |
36 |
| Peptidoglycan recognition by the innate immune system |
35 |
| Biology and regulation of IL-2: from molecular mechanisms to human therapy |
35 |
| Tissue-specific functions of invariant natural killer T cells |
35 |
| Metabolic interventions in the immune response to cancer |
34 |
| A cold-blooded view of adaptive immunity |
33 |
| Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection |
32 |
| New insights into the immune functions of complement |
32 |
| Interferon-lambda orchestrates innate and adaptive mucosal immune responses |
32 |
| Central CD4(+) T cell tolerance: deletion versus regulatory T cell differentiation |
32 |
| The full spectrum of human naive T cells |
32 |
| The dawn of vaccines for cancer prevention |
32 |
| How macrophages deal with death |
31 |
| Sleep and inflammation: partners in sickness and in health |
31 |
| The emerging role of ADAM metalloproteinases in immunity |
31 |
| Understanding the drivers of MHC restriction of T cell receptors |
30 |
| Pain and immunity: implications for host defence |
29 |
| CAR T cells for infection, autoimmunity and allotransplantation |
28 |
| Adaptive immune responses to primary and secondary dengue virus infections |
27 |
| Mucosal-associated invariant T cells and disease |
25 |
| Functional interactions between innate lymphoid cells and adaptive immunity |
25 |
| T cell-mediated immunity to malaria |
25 |
| T cells and the skin: from protective immunity to inflammatory skin disorders |
24 |
| Photoimmunology: how ultraviolet radiation affects the immune system |
24 |
| Synthetic immune niches for cancer immunotherapy |
24 |
| Engineering universal cells that evade immune detection |
23 |
| Histone deacetylase function in CD4(+) T cells |
23 |
| Perivascular macrophages in health and disease |
21 |
| Mechanisms underlying T cell ageing |
21 |
| Alternative mRNA splicing in cancer immunotherapy |
20 |
| Cytokine-mediated communication: a quantitative appraisal of immune complexity |
19 |
| Moving tuberculosis vaccines from theory to practice |
19 |
| Functional cure of HIV: the scale of the challenge |
19 |
| Diverse developmental pathways of intestinal intraepithelial lymphocytes |
18 |
| CARD-BCL-10-MALT1 signalling in protective and pathological immunity |
18 |
| Regulation of immune responses by tuft cells |
18 |
| Antibodies against Plasmodium falciparum malaria at the molecular level |
16 |
| DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer |
16 |
| Studying tissue macrophages in vitro: are iPSC-derived cells the answer? |
15 |
| To respond or not to respond - a personal perspective of intestinal tolerance |
15 |
| An early history of T cell-mediated cytotoxicity |
15 |
| Patrolling the vascular borders: platelets in immunity to infection and cancer |
14 |
| Nonhuman primate models of human viral infections |
14 |
| Sodium in the microenvironment regulates immune responses and tissue homeostasis |
14 |
| Statins: a viable candidate for host-directed therapy against infectious diseases |
13 |
| Antibodies and tuberculosis: finally coming of age? |
13 |
| How poverty affects diet to shape the microbiota and chronic disease |
12 |
| Tissue-specific immunopathology during malaria infection |
11 |
| Viral subversion of B cell responses within secondary lymphoid organs |
8 |
| Metabolic gatekeepers to safeguard against autoimmunity and oncogenic B cell transformation |
8 |
| At the intersection of DNA damage and immune responses |
8 |
| Breaking the law: unconventional strategies for antibody diversification |
8 |
| Models of immune selection for multi-locus antigenic diversity of pathogens |
7 |
| The evolving role of T-bet in resistance to infection |
4 |
| Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis |
4 |
| Genome organization in immune cells: unique challenges |
2 |
