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Structural insights into subtype-specific agonist recognition by sphingosine-1-phosphate receptor
Author: Yu, Leiye; Jiao, Haizhan; Pang, Bin; Ti, Rujuan; Gan, Bing; Qin, Zhaoyang; Wang, Jinxin; Zhu, Lizhe; Hu, Hongli; Ren, Ruobing
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003381
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Casein kinase 2-mediated phosphorylation of the splicing factor SF3B3 plays a key role in esophageal squamous cell carcinoma progressio
Author: Wang, Du-chuang; Li, Jia-yuan; Wang, Xiao-bing; Hu, Guo-sheng; Nie, Rui-chao; Zheng, Bin; He, Yao-hui; Liu, Wen
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003729
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The non-vesicular cholesterol transporter GRAMD1C is a pan-coronavirus antiviral targe
Author: Su, Zhelin; Fu, Zhen; Yang, Yichen; Fu, Yanan; Mo, Jingwen; Xu, Juan; Tan, Yubei; Xiang, Yixin; Shi, Yuejun; Xie, Shengsong; Sun, Limeng; Peng, Guiqing
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003736
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The m6Am methyltransferase PCIF1 promotes osteogenic differentiation of mesenchymal stem cells through stabilization of Wnt-related transcript
Author: Song, Wei; Su, Kuan-Jui; Pan, Zhehui; Zhang, Zhong; Yin, Qi; Lin, Weimin; Liu, Linfeng; Gong, Yun; Liang, Bocheng; Cai, Yimeng; Li, Qiwen; Shen, Hui; Deng, Hong-Wen; Yuan, Quan
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003739
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A dual-threshold system relying on multiple c-di-GMP metabolic enzymes controls cell fate of a cyanobacteriu
Author: Sun, Qing-Xue; Huang, Min; Yang, Yiling; Zeng, Xiaoli; Zhang, Cheng-Cai
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003750
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Human brains construct individualized global rankings from identical few-shot learning inpu
Author: Liu, Dongning; Wang, Muzhi; Luo, Huan
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003756
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Structure of the human P2X3 receptor reveals the basis for subtype-selective inhibition by sivopixan
Author: Zhao, Zhixuan; Wang, Dong-Ping; Zhang, Xin; Gao, Yuan; Xu, Hexin; Teng, Xinyu; Shen, Cheng; Chen, Jirui; Zhang, Jinru; Guo, Chang-Run; Hattori, Motoyuki
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 4, pp. -. DOI: 10.1371/journal.pbio.3003777
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Dynamic expectation strength and precision shape human pain perception through shared and dissociable α-oscillatory mechanism
Author: Li, Jia; Chen, Shihao; Zhang, Libo; Weng, Lingling; Lin, Xinxin; Tu, Yiheng; Peng, Weiwei
Journal: PLOS BIOLOGY. 2026; Vol. 24, Issue 3, pp. -. DOI: 10.1371/journal.pbio.3003675
