Alzheimers Research & Therapy

Alzheimers Research & Therapy

阿尔茨海默病研究与治疗

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer's disease 43
The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease 36
Advantages and disadvantages of the use of the CSF Amyloid (A) 42/40 ratio in the diagnosis of Alzheimer's Disease 33
FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac an active immunotherapy against tau protein pathology in Alzheimer's disease 25
Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE) 23
Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease 20
The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias 20
The rights of precision drug development for Alzheimer's disease 19
Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 x Tg-AD mice 19
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph 18
F-18-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes 17
Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's disease 17
Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic 17
Clinical prevalence of Lewy body dementia 17
In vivo quantification of neurofibrillary tangles with [F-18]MK-6240 17
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain 17
Synaptic proteins in CSF as potential novel biomarkers for prognosis in prodromal Alzheimer's disease 16
Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease 16
Comparative safety and effectiveness of cholinesterase inhibitors and memantine for Alzheimer's disease: a network meta-analysis of 41 randomized controlled trials 16
Gantenerumab reduces amyloid-beta plaques in patients with prodromal to moderate Alzheimer's disease: a PET substudy interim analysis 16
Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results 15
Vulnerability and resilience to Alzheimer's disease: early life conditions modulate neuropathology and determine cognitive reserve 15
Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease 15
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)study protocol for a randomized controlled trial 15
Alzheimer's disease master regulators analysis: search for potential molecular targets and drug repositioning candidates 15
A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation 14
Alzheimer disease pathology and the cerebrospinal fluid proteome 14
Systemic and central nervous system metabolic alterations in Alzheimer's disease 14
Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) 14
CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia 13
Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study 13
Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study 13
Alcohol use and dementia: a systematic scoping review 13
Amyloid beta-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation 13
Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE) 12
White matter microstructure is altered in cognitively normal middle-aged APOE-epsilon 4 12
Depression, subjective cognitive decline, and the risk of neurocognitive disorders 12
Variability in metabolic parameters and risk of dementia: a nationwide population-based study 12
Spatial patterns of white matter hyperintensities associated with Alzheimer's disease risk factors in a cognitively healthy middle-aged cohort 12
Brain glucose metabolism in Lewy body dementia: implications for diagnostic criteria 11
FDG-PET as an independent biomarker for Alzheimer's biological diagnosis: a longitudinal study 11
Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study 11
The EMIF-AD PreclinAD study: study design and baseline cohort overview 11
Consecutive sessions of transcranial direct current stimulation do not remediate visual hallucinations in Lewy body dementia: a randomised controlled trial 11
Is intracranial volume a suitable proxy for brain reserve? 11
Prevalence and risk of progression of preclinical Alzheimer's disease stages: a systematic review and meta-analysis 11
The quest for synergy between physical exercise and cognitive stimulation via exergaming in people with dementia: a randomized controlled trial 11
Brain and cognitive correlates of subjective cognitive decline-plus features in a population-based cohort 11
Early brain connectivity alterations and cognitive impairment in a rat model of Alzheimer's disease 11
Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome 10