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A comprehensive framework for the interpretation of TTN missense variant
Author: Di Feo, Maria Francesca; Rees, Martin; Lillback, Victoria; Kho, Ay Lin; Meybatova, Angelina; Holt, Mark; Jungbluth, Heinz; Muntoni, Francesco; Baranello, Giovanni; Sarkozy, Anna; Fiorillo, Chiara; Baratto, Serena; Bruno, Claudio; Traverso, Monica; Iacomino, Michele; Pedemonte, Marina; Brolatti, Noemi; Faravelli, Francesca; Zara, Federico; Mandara, G. M. Luana; Beggs, Alan H.; Genetti, Casie A.; Barraza-Flores, Pamela; Rodolico, Carmelo; Messina, Sonia; Schnabel, Franziska; Balogh, Istvan; Szakszon, Katalin; Sarv, Siiri; Ounap, Katrin; Ricci, Federica Silvia; Mussa, Alessandro; Malfatti, Edoardo; Bertini, Enrico Silvio; D'amico, Adele; Diodato, Daria; Catteruccia, Michela; Ravenscroft, Gianina; Johari, Mridul; Kurbatov, Sergei A.; Chausova, Polina; Murtazina, Aysylu; Kuchina, Anna; Shchagina, Olga; Drakos, Minas; Spilioti, Martha; Evangeliou, Athanasios E.; Zaganas, Ioannis; Zhong, Huahua; Luo, Sushan; Merlini, Luciano; Nguyen, Cam-Tu-Emilie; Tasca, Giorgio; Reeves, Tara; Morner, Stellan; Danielsson, Olof; Udd, Bjarne; Natera-de Benito, Daniel; Estevez Arias, Berta; Dhall, Aishwarya; Jassal, Bandana; Vishnu, Venugopalan Y.; Faruq, Mohammed; Gulati, Sheffali; Sharma, Mehar Chand; Kopcilova, Johana; Kramarova, Tereza; Zidkova, Jana; Gautel, Mathias; Savarese, Marco
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-026-01605-1
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Fitness Training for γδ T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organ
Author: Wang, Zhihua; Sun, Ting; Zhang, Yixin; Li, Yutao; Zhang, Chuankai; Dou, Xinwen; Deng, Xinyi; Li, Zhipeng; Zhu, Jingpu; Hong, Mingyang; Ran, Yi; Wang, Shu; Li, Liping; Zheng, Junjie; Wen, Cong; Zhang, Xi; Lu, Shu; Sagar; Mohanta, Sarajo K.; Habenicht, Andreas J. R.; Yin, Changjun
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-026-01613-1
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Cross-ancestry genome-wide association studies of liver function biomarkers uncover pleiotropic variants, systemic disease links and therapeutic target
Author: Yao, Wentao; Fan, Jingyi; Lu, Jing; Guo, Haiyan; Yu, Chengxiao; Wang, Xuehui; Wang, Yun; Zhang, Yu; Duan, Qingning; Cheng, Lihua; Zhou, Chen; Wang, Zhaohui; Dai, Juncheng; Ma, Hongxia; Zhang, Qun; Song, Ci; Shen, Hongbing
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-026-01606-0
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TiRank prioritizes phenotypic niches in tumor microenvironment for clinical biomarker discover
Author: Lin, Yuxiang; Huang, Zening; Lin, Ziyan; Lin, Yating; Song, Jinsheng; Luo, Ling; Chi, Jiayao; Zheng, Yeyang; Gao, Youxin; Lin, Junjie; Li, Xinyu; Liang, Chenyu; Zhang, Lei; Wang, Xinkang; Sun, Yuqin; Yu, Rongshan; Chen, Qiyue; Tong, Mengsha
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-026-01604-2
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Exploring phenotype-related single-cells through attention-enhanced representation learnin
Author: Wu, Qinhua; Ding, Junxiang; He, Ruikun; Hui, Lijian; Liu, Junwei; Li, Yixue
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-026-01598-x
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Multimodal-based analysis of single-cell ATAC-seq data enables highly accurate delineation of clinically relevant tumor cell subpopulation
Author: Xiong, Kewei; Wang, Wei; Ding, Ruofan; Luo, Dinglin; Qin, Yangmei; Zou, Xudong; Wang, Jiguang; Yu, Chen; Li, Lei
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-026-01599-w
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Detection of primary cancer types via fragment size selection in circulating cell-free extrachromosomal circular DN
Author: Fang, Jingwen; Luo, Songwen; Li, Shouzhen; Xu, Yehong; Wang, Jing; Shan, Benjie; Hu, Mingjun; Yu, Qiaoni; Zhang, Wen; Liu, Ke; Shao, Yunying; Yang, Jiaxuan; Zhou, Youyang; Xu, Guangtao; Yao, Xinfeng; Sun, Ruoming; Zhang, Mengyuan; Li, Kun; Xu, Xihai; Zhang, Yongliang; Zhang, Zhihong; Han, Xinghua; Pan, Yueyin; Guo, Chuang; Qu, Kun
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-025-01595-6
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Multi-omics reveals cholesterol-driven macrophage metabolic reprogramming and inflammation in chronic obstructive pulmonary diseas
Author: Ran, Xinru; Yang, Zhandong; Cheng, Li; Li, Weidong; Cui, Jieda; Huang, Peiyu; Wang, Zhongfang; Mao, Zhennan; Yi, Erkang; Tian, Yang; Li, Pan; Zhou, Yumin; Ran, Pixin; Guo, Feng
Journal: GENOME MEDICINE. 2026; Vol. 18, Issue 1, pp. -. DOI: 10.1186/s13073-025-01591-w
