| Antibody-drug conjugates: recent advances in conjugation and linker chemistries |
80 |
| Oral microbiomes: more and more importance in oral cavity and whole body |
72 |
| Structural and functional roles of ether lipids |
67 |
| The emerging role and targetability of the TCA cycle in cancer metabolism |
63 |
| IgG Fc engineering to modulate antibody effector functions |
39 |
| Current progress in innovative engineered antibodies |
38 |
| Gut microbiota derived metabolites in cardiovascular health and disease |
35 |
| The association of diet, gut microbiota and colorectal cancer: what we eat may imply what we get |
33 |
| Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy |
27 |
| Pharmacokinetics of monoclonal antibodies and Fc-fusion proteins |
26 |
| Phase I study of chimeric antigen receptor modified T cells in treating HER2-positive advanced biliary tract cancers and pancreatic cancers |
26 |
| Microbiota transplantation: concept, methodology and strategy for its modernization |
24 |
| T-cell receptor-engineered T cells for cancer treatment: current status and future directions |
22 |
| Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs |
20 |
| Carboxylesterases in lipid metabolism: from mouse to human |
17 |
| Pharmacomicrobiomics: a novel route towards personalized medicine? |
17 |
| Chemical screen identifies a geroprotective role of quercetin in premature aging |
17 |
| mTORC1 signaling in hepatic lipid metabolism |
15 |
| Sialylation is involved in cell fate decision during development, reprogramming and cancer progression |
15 |
| In vitro-engineered non-antibody protein therapeutics |
15 |
| New insight into inter-organ crosstalk contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) |
14 |
| Phage display screening of therapeutic peptide for cancer targeting and therapy |
14 |
| Release and uptake mechanisms of vesicular Ca2+ stores |
14 |
| Regeneration of functional alveoli by adult human SOX9(+) airway basal cell transplantation |
13 |
| RNA binding protein 24 deletion disrupts global alternative splicing and causes dilated cardiomyopathy |
12 |
| Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome |
12 |
| Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels |
12 |
| PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation |
10 |
| Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells |
10 |
| The role of ubiquitination and deubiquitination in the regulation of cell junctions |
9 |
| The SWI/SNF chromatin-remodeling factors BAF60a, b, and c in nutrient signaling and metabolic control |
9 |
| Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis |
9 |
| Targeting cancer stem cells by using chimeric antigen receptor-modified T cells: a potential and curable approach for cancer treatment |
9 |
| Solution structure of the RNA recognition domain of METTL3-METTL14 N-6-methyladenosine methyltransferase |
9 |
| Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers |
9 |
| Single-cell metagenomics: challenges and applications |
9 |
| Single-cell transcriptomics reveals gene signatures and alterations associated with aging in distinct neural stem/progenitor cell subpopulations |
9 |
| Molecular and functional analysis of monoclonal antibodies in support of biologics development |
8 |
| Remodeling of host membranes during herpesvirus assembly and egress |
8 |
| Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo |
8 |
| C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death |
8 |
| Mitochondrion-processed TERC regulates senescence without affecting telomerase activities |
8 |
| RIG-I: a multifunctional protein beyond a pattern recognition receptor |
8 |
| IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis |
7 |
| Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition |
7 |
| NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase eta in response to oxidative DNA damage |
7 |
| Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1 |
6 |
| Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer's disease |
6 |
| A binding-block ion selective mechanism revealed by a Na/K selective channel |
6 |
| Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate |
6 |
