Clinical Epigenetics

Clinical Epigenetics

临床表观遗传学

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage 82
The role and mechanisms of action of microRNAs in cancer drug resistance 69
Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma 37
The timeline of epigenetic drug discovery: from reality to dreams 36
Epigenetic therapy for ovarian cancer: promise and progress 32
Air pollution and DNA methylation: effects of exposure in humans 26
DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD- CTLA- TIM- LAG- TIGIT, and PD-L1 genes in human primary breast cancer 26
Association of four imprinting disorders and ART 24
Epigenetics in cancer therapy and nanomedicine 23
The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis 23
The emerging role of epigenetics in human autoimmune disorders 23
Exposure to NO CO, and PM2.5 is linked to regional DNA methylation differences in asthma 21
Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism 20
Promoter methylation of ADAMTS1 and BNC1 as potential biomarkers for early detection of pancreatic cancer in blood 20
Control of viral infections by epigenetic-targeted therapy 19
H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia 17
Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma 17
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease 16
Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study 16
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health 15
A five-DNA methylation signature act as a novel prognostic biomarker in patients with ovarian serous cystadenocarcinoma 15
miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway 15
The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genes 14
Particulate matter exposure shapes DNA methylation through the lifespan 14
Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH2 14
Hsa_circRNA_0054633 is highly expressed in gestational diabetes mellitus and closely related to glycosylation index 14
DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling 13
Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis 13
Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer 13
Early-life exposure to severe famine is associated with higher methylation level in the IGF2 gene and higher total cholesterol in late adulthood: the Genomic Research of the Chinese Famine (GRECF) study 13
Long non-coding RNAs: implications in targeted diagnoses, prognosis, and improved therapeutic strategies in human non-and triple-negative breast cancer 13
Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants 12
Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots 12
Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome 12
MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development 12
Emerging roles of H3K9me SETDB1 and SETDB2 in therapy-induced cellular reprogramming 12
DNA methylation as a predictor of fetal alcohol spectrum disorder 12
Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia 12
Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C 12
Epigenetic regulation of MAGE family in human cancer progression-DNA methylation, histone modification, and non-coding RNAs 12
Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype? 12
Urine cell-based DNA methylation classifier for monitoring bladder cancer 12
DNA methylation signature of human hippocampus in Alzheimer's disease is linked to neurogenesis 12
CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway 11
Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin 11
DNA methylome profiling of granulosa cells reveals altered methylation in genes regulating vital ovarian functions in polycystic ovary syndrome 11
Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta 11
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood 11
Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus 10
Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes 10