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Safety, efficacy, and distal nerve Schwann cell biodistribution in mice and NHPs to support translation of AAV9 RNAi therapy for CMT1
Author: Stavrou, Marina; Wallace, Lindsay M.; Thangaraj, Merlin P.; Taylor, Noah K.; Kagiava, Alexia; Papacharalambous, Revekka; Mcallister, Cynthia; Zender, Gloria; Saad, Nizar Y.; Bayazit, M. Bilal; Heslegrave, Amanda; Tryfonos, Christina; Richter, Jan; Zetterberg, Henrik; Price, Brian; Salzman, Rachel; Kleopa, Kleopas A.; Harper, Scott Q
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102881
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Multi-layer molecular profiling defines an immune-active colorectal cancer subtype with therapeutic relevanc
Author: Zou, Miao; Wang, Zuxiang; Zhou, Wenyang; Xue, Guangfu; Hui, Yi; Pang, Fenglan; Tan, Renjie; Xu, Zhaochun; Jin, Xiyun; Sun, Haoxiu; Wang, Pingping; Jiang, Qinghua
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102907
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Unlocking the potential of mRNA nanomedicines for comprehensive fibrosis therap
Author: Yang, Yue; Li, Chaofu; Xiong, Weidong; Li, Chuanwei; Xiao, Jun
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102917
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c-Jun in neurodegeneration: A key transcriptional regulator with therapeutic implication
Author: Khan, Faiz Ali; Khan, Hizbullah; Awan, Usman Ayub; Nurahmat, Mammat; Nabijan, Mohammadtursun; Abduwaki, Muhammadjan; Dong, Jingcheng
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102874
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TiSMeD: A tissue-specific methylation and expression database for biomarker and translational application
Author: Cheng, Jiao; Lin, Zhe; Wu, Lvying; Li, Qianying; Yin, Huajun; Wang, Hao; Chen, Hao; Chen, Xiaoyan; Ji, Zhi-Liang
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102884
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TIPE2 gene knockdown in mice attenuates experimental colitis by diminishing inflammatory cell infiltratio
Author: Tang, Yexiao; Li, Ping; Li, Minghui; Zhang, Pengchao; Lu, Zhen; Qiao, Hang; Wei, Jing; Xu, Zhiming; Wan, Xiaochun; Xu, Shu; Chen, Youhai H.; Zhang, Guizhong
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102887
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Potential effects of endogenous RNA/DNA hybrids on CRISPR-Cas9-mediated homology-directed repai
Author: Puzzo, Francesco; Bayram, Batuhan; Macaubas, Claudia; Lin, Angela; Jang, Hagoon; Zhang, Feijie; Mellins, Elizabeth; Kay, Mark A
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 2, pp. -. DOI: 10.1016/j.omtn.2026.102880
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Rabies lyssavirus phosphoprotein possesses RNA duplex-unwinding activitie
Author: Mu, Jingfang; Wang, Caiqian; Shu, Ting; Xiong, Xiaobei; Ren, Yujie; Gong, Rui; Zhao, Ling; Zhou, Xi
Journal: MOLECULAR THERAPY NUCLEIC ACIDS. 2026; Vol. 37, Issue 1, pp. -. DOI: 10.1016/j.omtn.2026.102863
