| The hypoxic tumour microenvironment |
113 |
| Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases |
62 |
| Double agents: genes with both oncogenic and tumor-suppressor functions |
28 |
| The crosstalk between STAT3 and p53/RAS signaling controls cancer cell metastasis and cisplatin resistance via the Slug/MAPK/PI3K/AKT-mediated regulation of EMT and autophagy |
21 |
| Inhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancer |
21 |
| Epigenetic regulation of lung cancer cell proliferation and migration by the chromatin remodeling protein BRG1 |
20 |
| Tumor-derived exosomes induce PD1(+) macrophage population in human gastric cancer that promotes disease progression |
19 |
| ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage |
19 |
| An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance |
18 |
| The ribosome, (slow) beating heart of cancer (stem) cell |
18 |
| Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer |
18 |
| LncRNA HOXA-AS3 confers cisplatin resistance by interacting with HOXA3 in non-small-cell lung carcinoma cells |
17 |
| Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness |
15 |
| DeepCC: a novel deep learning-based framework for cancer molecular subtype classification |
15 |
| CD36 plays a critical role in proliferation, migration and tamoxifen-inhibited growth of ER-positive breast cancer cells |
15 |
| miR-330-5p targets SPRY2 to promote hepatocellular carcinoma progression via MAPK/ERK signaling |
15 |
| SOX2 recruits KLF4 to regulate nasopharyngeal carcinoma proliferation via PI3K/AKT signaling |
15 |
| Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression |
14 |
| Unwrapping the genomic characteristics of urothelial bladder cancer and successes with immune checkpoint blockade therapy |
14 |
| CBX2 identified as driver of anoikis escape and dissemination in high grade serous ovarian cancer |
13 |
| Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56 |
13 |
| Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1(+) TAM expansion |
13 |
| Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death |
12 |
| Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB |
12 |
| HOXC8 promotes proliferation and migration through transcriptional upregulation of TGF beta 1 in non-small cell lung cancer |
12 |
| Blocking CXCLs-CXCR2 axis in tumor-stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment |
11 |
| A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma |
11 |
| The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer |
11 |
| Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma |
11 |
| Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability |
10 |
| Dihydroartemisinin inhibits prostate cancer via JARID2/miR-7/miR-34a-dependent downregulation of Axl |
10 |
| Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma |
10 |
| ZFHX3 is indispensable for ER beta to inhibit cell proliferation via MYC downregulation in prostate cancer cells |
9 |
| Reciprocal regulatory mechanism between miR-214-3p and FGFR1 in FGFR1-amplified lung cancer |
9 |
| Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4 |
9 |
| Upregulation of SALL4 by EGFR activation regulates the sternness of CD44-positive lung cancer |
9 |
| Cancer cell-derived von Willebrand factor enhanced metastasis of gastric adenocarcinoma |
9 |
| TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/beta-catenin pathway |
9 |
| Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth |
9 |
| Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies |
9 |
| MicroRNA-transcription factor network analysis reveals miRNAs cooperatively suppress RORA in oral squamous cell carcinoma |
9 |
| Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia |
8 |
| A negative feedback loop between XBP1 and Fbw7 regulates cancer development |
8 |
| Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma |
8 |
| Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects |
8 |
| Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer |
8 |
| Notch3 inhibits epithelial-mesenchymal transition in breast cancer via a novel mechanism, upregulation of GATA-3 expression |
8 |
| Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1 |
8 |
| Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway |
8 |
| NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest |
8 |
