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Paeoniflorin alleviates hypobaric hypoxiatriggered lung injury through targeting MEK2 to modulate ERK2-SGK1 signalin
Author: Wu, Zhenhui; Wang, Yihao; Wang, Renjie; Gao, Rong; Li, Shubei; Tu, Bodan; Yin, Xiubing; Li, Maoxing; Zhou, Wei; Xu, Huanhua; Wu, Zhenfeng; Ma, Zengchun; Tang, Xianglin; Xiao, Chengrong; Gao, Yue
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1466-1488. DOI: 10.1016/j.apsb.2025.12.024
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Targeting immunosuppressive network in glioblastoma: Emerging strategies to overcome immunodeficiency and enhance therapeutic efficac
Author: Zhou, Songlei; Zhang, Xiaokun; Lin, Jiayi; Ma, Fenfen; Chen, Hongzhuan; Chen, Jun; Luan, Xin
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1272-1291. DOI: 10.1016/j.apsb.2026.01.015
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Mechanistic insights into ligand selectivity in m-and δ-opioid receptors beyond the message-address conceptual framewor
Author: Zhang, Xin; Song, Hongyan; Chen, Ruofan; Kong, Xinran; Wang, Jin; Li, Xinghua; Yu, Ye
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1530-1549. DOI: 10.1016/j.apsb.2025.11.039
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AI-integrated microfluidics for drug screening: From single cell to organ-on-a-chi
Author: Yin, Hongyun; Li, Zheyu; Shen, Zinuo; Wang, Shiying; Du, Na; Cheng, Shibo; Zhou, Jie; Li, Yutao; Jia, Yanwei; Li, Ying
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1175-1200. DOI: 10.1016/j.apsb.2026.01.001
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Inhibition of PGK1 enhances sensitivity to tyrosine kinase inhibitor in T315I-mutant leukemi
Author: Wang, Huijing; Jiang, Fengyu; Pan, An; Jin, Chenlong; Xue, Yangyang; Liu, Wenjie; Gu, Renjun; Zhou, Yanyu; Shen, Qiuhong; Ma, Tonghui; Yu, Xiaoxuan
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1449-1465. DOI: 10.1016/j.apsb.2025.12.039
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Targeting RNA binding proteins with small-molecule inhibitors: Advances, challenges, and therapeutic opportunitie
Author: Shi, Yuning; Feng, Dazhi; Zhou, Jieya; Liu, Lihua; Li, Xinnan; Yuan, Zhenwei; Wu, Jianbing; Yao, Hong
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1292-1335. DOI: 10.1016/j.apsb.2025.12.010
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TeroACT: A terpenoid bioactivity landscape and discovery platfor
Author: Shen, Xiaojuan; Yan, Shijia; Kang, Xu; Xu, Kangwei; Jian, Yongxing; Zeng, Tao; Wan, Guohui; Wu, Ruibo
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1233-1249. DOI: 10.1016/j.apsb.2025.12.036
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A review of recent advances in generative artificial intelligence models for biomolecular science
Author: Jiang, Jian; Li, Daixin; Wang, Guilin; Hayes, Nicole; Shi, Yazhou; Qiu, Huahai; Zhang, Bengong; Zhou, Tianshou; Wei, Guo-Wei
Journal: ACTA PHARMACEUTICA SINICA B. 2026; Vol. 16, Issue 3, pp. 1201-1218. DOI: 10.1016/j.apsb.2025.12.012
