| A perspective on multi-target drug discovery and design for complex diseases |
89 |
| Analyses of repeated failures in cancer therapy for solid tumors: poor tumor-selective drug delivery, low therapeutic efficacy and unsustainable costs |
64 |
| The role of CD133 in cancer: a concise review |
45 |
| Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges |
35 |
| Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms |
31 |
| Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer |
30 |
| Recent advances in hyaluronic acid based therapy for osteoarthritis |
28 |
| Oncolytic viruses and checkpoint inhibitors: combination therapy in clinical trials |
27 |
| Combination therapy to checkmate Glioblastoma: clinical challenges and advances |
27 |
| Pancreatic cancer microenvironment: a current dilemma |
21 |
| Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma |
21 |
| Lipidomics unveils the complexity of the lipidome in metabolic diseases |
20 |
| Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options |
18 |
| The gut microbiome and response to immune checkpoint inhibitors: preclinical and clinical strategies |
18 |
| Epigenetics of hepatocellular carcinoma |
17 |
| Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy |
15 |
| Pros and cons of mouse models for studying osteoarthritis |
13 |
| Cell membrane protein functionalization of nanoparticles as a new tumor-targeting strategy |
11 |
| Cytokines, breast cancer stem cells (BCSCs) and chemoresistance |
10 |
| New therapeutic targets for cancer: the interplay between immune and metabolic checkpoints and gut microbiota |
10 |
| Comparison of paired human nasal and bronchial airway epithelial cell responses to rhinovirus infection and IL-13 treatment |
9 |
| From fiction to science: clinical potentials and regulatory considerations of gene editing |
9 |
| The role of environmental exposure to non-cigarette smoke in lung disease |
9 |
| Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis |
9 |
| Combination systemic therapies with immune checkpoint inhibitors in pancreatic cancer: overcoming resistance to single-agent checkpoint blockade |
8 |
| The significance of microbiome in personalized medicine |
8 |
| The dual functional role of MicroRNA-18a (miR-18a) in cancer development |
8 |
| Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes Monique |
8 |
| Alk5/Runx1 signaling mediated by extracellular vesicles promotes vascular repair in acute respiratory distress syndrome |
8 |
| The role of liver microenvironment in hepatic metastasis |
8 |
| Cell toxicity mechanism and biomarker |
7 |
| Application of metabolomics to drug discovery and understanding the mechanisms of action of medicinal plants with anti-tuberculosis activity |
7 |
| Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer |
7 |
| The impact of modifiable risk factor reduction on childhood asthma development |
6 |
| Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk |
6 |
| The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy |
6 |
| Cancer; an induced disease of twentieth century! Induction of tolerance, increased entropy and 'Dark Energy': loss of biorhythms (Anabolism v. Catabolism) |
5 |
| Sites of synchronous distant metastases and prognosis in prostate cancer patients with bone metastases at initial diagnosis: a population-based study of 643 patients |
4 |
| HIV-exposed uninfected infants: elevated cord blood Interleukin 8 (IL-8) is significantly associated with maternal HIV infection and systemic IL-8 in a Kenyan cohort |
3 |
| Debutant iOS app and gene-disease complexities in clinical genomics and precision medicine |
3 |
| Anti-inflammatory and antiplatelet effects of non-vitamin K antagonist oral anticoagulants in acute phase of ischemic stroke patients |
3 |
| Mesenchymal stem cell-gut microbiota interaction in the repair of inflammatory bowel disease: an enhanced therapeutic effect |
3 |
| Circulating free DNA concentration as a marker of disease recurrence and metastatic potential in lung cancer |
3 |
| Endogenous expression mapping of malignant melanoma by mass spectrometry imaging |
2 |
| Systemic treatment for lung carcinoids: from bench to bedside |
2 |
| The use of leukocytes' secretome to individually target biological therapy in autoimmune arthritis: a case report |
2 |
| EGFR plasma mutation in prediction models for resistance with EGFR TKI and survival of non-small cell lung cancer |
2 |
| Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator |
2 |
| Feasibility study of using high-throughput drug sensitivity testing to target recurrent glioblastoma stem cells for individualized treatment |
1 |
| Role of medical and molecular imaging in COPD |
1 |
