| Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state |
18 |
| Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC |
14 |
| Metabolomics of oncogene-specific metabolic reprogramming during breast cancer |
11 |
| SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia |
10 |
| Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities |
10 |
| Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation |
9 |
| Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells |
8 |
| Stratification of cancer and diabetes based on circulating levels of formate and glucose |
7 |
| Protein interaction and functional data indicate MTHFD2 involvement in RNA processing and translation |
6 |
| CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain |
6 |
| Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer |
6 |
| Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA |
6 |
| Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner |
6 |
| The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer |
6 |
| Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice |
5 |
| Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer |
5 |
| Hexokinase 2 is dispensable for T cell-dependent immunity |
5 |
| Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma |
4 |
| A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers |
4 |
| Characterization of the molecular changes associated with the overexpression of a novel epithelial cadherin splice variant mRNA in a breast cancer model using proteomics and bioinformatics approaches: identification of changes in cell metabolism and an increased expression of lactate dehydrogenase B |
4 |
| CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism |
4 |
| CD38 is methylated in prostate cancer and regulates extracellular NAD(+) |
4 |
| p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant |
3 |
| Activation of pro-survival metabolic networks by 25(OH)(2)D-3 does not hamper the sensitivity of breast cancer cells to chemotherapeutics |
3 |
| PKM2 is not required for pancreatic ductal adenocarcinoma |
3 |
| Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9) |
3 |
| Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells |
2 |
| HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells |
1 |
| Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors |
1 |
| A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin |
1 |
| Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate |
0 |
| A systematic flux analysis approach to identify metabolic vulnerabilities in human breast cancer cell lines |
0 |
