| Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs |
21 |
| Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease |
20 |
| Memantine protects thalamocortical hyper-glutamatergic transmission induced by NMDA receptor antagonism via activation of system xc(-) |
12 |
| Vancomycin therapeutic drug monitoring and population pharmacokinetic models in special patient subpopulations |
11 |
| MicroRNAs in non-small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential |
10 |
| Revisiting the putative role of heme as a trigger of inflammation |
10 |
| Pharmacological properties of revefenacin (TD-4208), a novel, nebulized long-acting, and lung selective muscarinic antagonist, at human recombinant muscarinic receptors and in rat, guinea pig, and human isolated airway tissues |
9 |
| The safety, tolerability, and pharmacokinetic profile of GSK283 a novel 2nd generation HIV maturation inhibitor, as assessed in healthy subjects |
8 |
| Depressive disorders: Treatment failures and poor prognosis over the last 50 years |
8 |
| The sodium pump and digitalis drugs: Dogmas and fallacies |
8 |
| The pharmacology and therapeutic applications of monoclonal antibodies |
8 |
| Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark |
8 |
| Expression of cytochrome P450 mRNAs in Type II alveolar cells from subjects with chronic obstructive pulmonary disease |
7 |
| Ajulemic acid: potential treatment for chronic inflammation |
7 |
| Drug conjugates-an emerging approach to treat breast cancer |
7 |
| Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition |
6 |
| Rezafungin treatment in mouse models of invasive candidiasis and aspergillosis: Insights on the PK/PD pharmacometrics of rezafungin efficacy |
6 |
| Anxiety- and activity-related effects of paracetamol on healthy and neuropathic rats |
6 |
| 15-epoxyeicosatrienoic acid produced by cytochrome P450s enhances neurite outgrowth of PC12 and rat hippocampal neuronal cells |
6 |
| Therapeutic potential of adenosine kinase inhibition-Revisited |
6 |
| Propranolol pharmacokinetics in infants treated for Infantile Hemangiomas requiring systemic therapy: Modeling and dosing regimen recommendations |
6 |
| Race affects SVR12 in a large and ethnically diverse hepatitis C-infected patient population following treatment with direct-acting antivirals: Analysis of a single-center Department of Veterans Affairs cohort |
5 |
| Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes |
5 |
| Machine learning of big data in gaining insight into successful treatment of hypertension |
5 |
| Enantioselective pharmacokinetics of tramadol and its three main metabolites; impact of CYP2D CYP2B and CYP3A4 genotype |
5 |
| Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes |
5 |
| Pharmacokinetic variability of beta-adrenergic blocking agents used in cardiology |
5 |
| MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions |
5 |
| l-alpha-Lysophosphatidylinositol (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK-dependent pathway |
5 |
| Pharmacokinetic equivalence, comparable safety, and immunogenicity of an adalimumab biosimilar product (M923) to Humira in healthy subjects |
4 |
| Tolerability, pharmacokinetics, and pharmacodynamics of mirogabalin in healthy subjects: Results from phase 1 studies |
4 |
| Methods for the assessment of selection bias in drug safety during pregnancy studies using electronic medical data |
4 |
| A structured literature review of interventions used in the management of nonalcoholic steatohepatitis (NASH) |
4 |
| The human NMDA receptor GluN2A(N615K) variant influences channel blocker potency |
4 |
| Quantitative systems toxicology (QST) reproduces species differences in PF-04895162 liver safety due to combined mitochondrial and bile acid toxicity |
4 |
| Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases |
4 |
| Utility of Glycosylated TIMP3 molecules: Inhibition of MMPs and TACE to improve cardiac function in rat myocardial infarct model |
4 |
| Effect of a mitochondrial-targeted coenzyme Q analog on pancreatic -cell function and energetics in high fat fed obese mice |
4 |
| Inconsistencies in dosage practice in children with overweight or obesity: A retrospective cohort study |
4 |
| Pharmacokinetics and pharmacodynamics of the cytolytic anti-CD38 human monoclonal antibody TAK-079 in monkey - model assisted preparation for the first in human trial |
4 |
| A pharmacokinetic study of radiprodil oral suspension in healthy adults comparing conventional venous blood sampling with two microsampling techniques |
3 |
| Combined antitumoral effects of pretubulysin and methotrexate |
3 |
| Treatment with new organic nitrites in pulmonary hypertension of acute experimental pulmonary embolism |
3 |
| Pharmacokinetics and safety of Enasidenib following single oral doses in Japanese and Caucasian subjects |
3 |
| Synergistic interaction between the agonism of cebranopadol at nociceptin/orphanin FQ and classical opioid receptors in the rat spinal nerve ligation model |
3 |
| The drug interaction potential of daprodustat when coadministered with pioglitazone, rosuvastatin, or trimethoprim in healthy subjects |
3 |
| Reduced alcohol-seeking in male offspring of sires exposed to alcohol self-administration followed by punishment-imposed abstinence |
3 |
| Dietary tetrahydrocurcumin reduces renal fibrosis and cardiac hypertrophy in 5/6 nephrectomized rats |
3 |
| Effects of magnesium chloride on invitro cholinesterase and ATPase poisoning by organophosphate (chlorpyrifos) |
3 |
| Effect of P21-activated kinase 1 (PAK-1) inhibition on cancer cell growth, migration, and invasion |
3 |
