Synthetic And Systems Biotechnology

Synthetic And Systems Biotechnology

合成和系统生物技术

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Activation of microbial secondary metabolic pathways: Avenues and challenges 25
CRISPR-Cas9/Cas12a biotechnology and application in bacteria 17
A living foundry for Synthetic Biological Materials: A synthetic biology roadmap to new advanced materials 15
Systematically investigating the key features of the DNase deactivated Cpf1 for tunable transcription regulation in prokaryotic cells 13
Simple glycolipids of microbes: Chemistry, biological activity and metabolic engineering 12
Therapeutic applications of genetic code expansion 11
Engineering and modification of microbial chassis for systems and synthetic biology 11
Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate 10
Methods to reduce variability in E. Coli-based cell-free protein expression experiments 8
Cell-free synthetic biology for in vitro biosynthesis of pharmaceutical natural products 8
Efficient editing DNA regions with high sequence identity in actinomycetal genomes by a CRISPR-Cas9 system 8
Simultaneously down-regulation of multiplex branch pathways using CRISPRi and fermentation optimization for enhancing beta-amyrin production in Saccharomyces cerevisiae 8
Improved production of docosahexaenoic acid in batch fermentation by newly-isolated strains of Schizochytrium sp. and Thraustochytriidae sp. through bioprocess optimization 7
Cell-free protein synthesis enabled rapid prototyping for metabolic engineering and synthetic biology 7
Regulation of antibiotic biosynthesis in actinomycetes: Perspectives and challenges 7
Conversion of D-glucose to L-lactate via pyruvate by an optimized cell-free enzymatic biosystem containing minimized reactions 7
An in vitro synthetic biology platform for emerging industrial biomanufacturing: Bottom-up pathway design 6
Rational and semi-rational engineering of cytochrome P450s for biotechnological applications 6
Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp. HB-J378 6
Genomic and transcriptional changes in response to pinene tolerance and overproduction in evolved Escherichia coli 6
The phage T4 DNA ligase mediates bacterial chromosome DSBs repair as single component non-homologous end joining 6
Cell-free synthesis of stable isotope-labeled internal standards for targeted quantitative proteomics 5
Metabolic engineering of Corynebacterium glutamicum S9114 based on whole-genome sequencing for efficient N-acetylglucosamine synthesis 5
Resistance mechanisms and reprogramming of microorganisms for efficient biorefinery under multiple environmental stresses 5
Resolution of deep divergence of club fungi (phylum Basidiomycota) 5
Blossom of CRISPR technologies and applications in disease treatment 5
Comparative functional genomics of the acarbose producers reveals potential targets for metabolic engineering 4
Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis 4
Miniaturisation of high-throughput plasmid DNA library preparation for next-generation sequencing using multifactorial optimisation 4
Simplified methodology for a modular and genetically expanded protein synthesis in cell-free systems 4
Phosphate limitation increases coenzyme Q(10) production in industrial Rhodobacter sphaeroides HY01 4
Efficient biosynthesis of 2-keto-D-gluconic acid by fed-batch culture of metabolically engineered Gluconobacter japonicus 4
Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001 3
Synergistic drug combinations prediction by integrating pharmacological data 3
Streptomyces avermitilis industrial strain as cell factory for Ivermectin B1a production 3
Crystal structure of the condensation domain from lovastatin polyketide synthase 3
SCO a TetR family regulator, is responsible for osmotic stress in Streptomyces coelicolor 3
The functional differentiation of the post-PKS tailoring oxygenases contributed to the chemical diversities of atypical angucyclines 3
Substrate specificity of the cypemycin decarboxylase CypD 2
A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue 2
Synthetic immunology: T-cell engineering and adoptive immunotherapy 2
Engineering metabolic pathways in Amycolatopsis japonicum for the optimization of the precursor supply for heterologous brasilicardin congeners production 2
Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering 2
Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228 2
Benchmarking two Saccharomyces cerevisiae laboratory strains for growth and transcriptional response to methanol 2
Design and synthesis of synthetic UP elements for modulation of gene expression in Escherichia coli 2
New KAT6 inhibitors induce senescence and arrest cancer growth 1
A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in Streptomyces hygrospinosus var. beijingensis 1
Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049 1
Engineering strong and stress-responsive promoters in Bacillus subtilis by interlocking sigma factor binding motifs 1