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In situ expansion and reprogramming of Kupffer cells elicit potent tumoricidal immunity against liver metastasis
Author: Liu, Wei; Zhou, Xia; Yao, Qi; Chen, Chen; Zhang, Qing; Ding, Keshuo; Li, Lu; Zeng, Zhutian
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 8, pp. -. DOI: 10.1172/JCI157937
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Thioredoxin 1 promotes autophagy through transnitrosylation of Atg7 during myocardial ischemia
Author: Nagarajan, Narayani; Oka, Shin-ichi; Nah, Jihoon; Wu, Changgong; Zhai, Peiyong; Mukai, Risa; Xu, Xiaoyong; Kashyap, Sanchita; Huang, Chun-Yang; Sung, Eun-Ah; Mizushima, Wataru; Titus, Allen Sam; Takayama, Koichiro; Mourad, Youssef; Francisco, Jamie; Liu, Tong; Chen, Tong; Li, Hong; Sadoshima, Junichi
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 3, pp. -. DOI: 10.1172/JCI162326
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Glucose- and glutamine-dependent bioenergetics sensitize bone mechanoresponse after unloading by modulating osteocyte calcium dynamics
Author: Liu, Xiyu; Yan, Zedong; Cai, Jing; Wang, Dan; Yang, Yongqing; Ding, Yuanjun; Shao, Xi; Hao, Xiaoxia; Luo, Erping; Guo, Edward; Luo, Peng; Shen, Liangliang; Jing, Da
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 3, pp. -. DOI: 10.1172/JCI164508
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Mini-dCas13X-mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy
Author: Li, Guoling; Jin, Ming; Li, Zhifang; Xiao, Qingquan; Lin, Jiajia; Yang, Dong; Liu, Yuanhua; Wang, Xing; Xie, Long; Ying, Wenqin; Wang, Haoqiang; Zuo, Erwei; Shi, Linyu; Wang, Ning; Chen, Wanjin; Xu, Chunlong; Yang, Hui
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 3, pp. -. DOI: 10.1172/JCI162809
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A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
Author: He, Shufang; Zambelli, Vanessa O.; Sinharoy, Pritam; Brabenec, Laura; Bian, Yang; Rwere, Freeborn; Hell, Rafaela C. R.; Neto, Beatriz Stein; Hung, Barbara; Yu, Xuan; Zhao, Meng; Luo, Zhaofei; Wu, Chao; Xu, Lijun; Svensson, Katrin J.; McAllister, Stacy L.; Stary, Creed M.; Wagner, Nana-Maria; Zhang, Ye; Gross, Eric R.
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 3, pp. -. DOI: 10.1172/JCI163735
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UBC9 deficiency enhances immunostimulatory macrophage activation and subsequent antitumor T cell response in prostate cancer
Author: Xiao, Jun; Sun, Fei; Wang, Ya-Nan; Liu, Bo; Zhou, Peng; Wang, Fa-Xi; Zhou, Hai-Feng; Ge, Yue; Yue, Tian-Tian; Luo, Jia-Hui; Yang, Chun-Liang; Rong, Shan-Jie; Xiong, Ze-Zhong; Ma, Sheng; Zhang, Qi; Xun, Yang; Yang, Chun-Guang; Luan, Yang; Wang, Shao-Gang; Wang, Cong-Yi; Wang, Zhi-Hua
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 4, pp. -. DOI: 10.1172/JCI158352
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SHP2 deneddylation mediates tumor immunosuppression in colon cancer via the CD47/SIRP alpha axis
Author: Li, Yiqing; Zhou, Hui; Liu, Pan; Lv, Dandan; Shi, Yichun; Tang, Bufu; Xu, Jiaqi; Zhong, Tingting; Xu, Wangting; Zhang, Jie; Zhou, Jianying; Ying, Kejing; Zhao, Yongchao; Sun, Yi; Jiang, Zhinong; Cheng, Hongqiang; Zhang, Xue; Ke, Yuehai
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 4, pp. -. DOI: 10.1172/JCI162870
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Butyrate ameliorates quinolinic acid-induced cognitive decline in obesity models
Author: Ge, Xing; Zheng, Mingxuan; Hu, Minmin; Fang, Xiaoli; Geng, Deqin; Liu, Sha; Wang, Li; Zhang, Jun; Guan, Li; Zheng, Peng; Xie, Yuanyi; Pan, Wei; Zhou, Menglu; Zhou, Limian; Tang, Renxian; Zheng, Kuiyang; Yu, Yinghua; Huang, Xu-Feng
Journal: JOURNAL OF CLINICAL INVESTIGATION. 2023; Vol. 133, Issue 4, pp. -. DOI: 10.1172/JCI154612
