Journal Of Clinical Investigation

Journal Of Clinical Investigation

临床研究杂志

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators 164
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes 119
Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade 114
Mechanisms and functions of cellular senescence 106
B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma 96
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies 83
Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine 79
Mitochondrial dysfunction in pathophysiology of heart failure 73
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart 72
Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression 69
PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression 69
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma 58
Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging 55
Fructose metabolism and metabolic disease 51
CD19 CAR T cell product and disease attributes predict leukemia remission durability 49
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer 48
Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma 48
Regulatory T cells in embryo implantation and the immune response to pregnancy 47
Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives 46
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction 45
Insulin resistance causes inflammation in adipose tissue 45
Early B cell changes predict autoimmunity following combination immune checkpoint blockade 45
Extracellular matrix as a driver of progressive fibrosis 45
Fibroblast heterogeneity: implications for human disease 44
L-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans 44
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy 44
Resolution of organ fibrosis 43
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target 42
Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma 42
Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy 41
Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation 41
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 40
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers 40
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer 40
Emerging strategies for combination checkpoint modulators in cancer immunotherapy 40
Functional significance of the platelet immune receptors GPVI and CLEC-2 39
The role of macrophages in the resolution of inflammation 39
Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy 38
Circulating and intrahepatic antiviral B cells are defective in hepatitis B 38
Epithelial cell derived cytokines: more than just signaling the alarm 36
An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia 36
PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection 35
Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation 35
Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers 35
microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential 35
Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus 35
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion 35
The role of mitochondria in aging 34
Expression of mutant Sftpc in murine alveolar epithelia drives spontaneous lung fibrosis 34
Strategies targeting cellular senescence 34