-
Lipid nanoparticle-delivered ornithine transcarbamylase mRNA alleviates liver fibrosis in preclinical model
Author: Zhai, Dongqing; Ni, Jiaping; Shao, Xianyu; Zhao, Weijun; Chen, Yuenan; Fan, Kailin; Li, Jingtong; Shen, Yumeng; Lin, Ang; Hu, Weiwei; Yang, Yong
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001708
-
Deep learning-assisted tumor radiomic dynamics on MRI predict pathological complete response in HCC undergoing immune-based therapy followed by hepatectom
Author: Zhou, Shi-Qi; Wang, Lu-Na; Wu, Li-Fang; Sun, Li-Yu; Yang, Yu-Chen; Yang, Zi-Yue; Wang, Zi-Yi; He, Tian; Li, Fei; Chen, Ling-Li; Li, Hui; Zhu, Xiao-Dong; Shen, Ying-Hao; Huang, Cheng; Ji, Yuan; Gao, Qiang; Zhou, Jian; Jia, Fan; Chen, Yong-Jun; Song, Tian-Qiang; Xu, Bin; Sun, Hui-Chuan
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001724
-
ECM1 produced by hepatic stellate cells serves as a gatekeeper of liver homeostasis in hepatic fibrosi
Author: Yang, Aiting; Yan, Xuzhen; Wang, Yiwen; Han, Qi; Tong, Xiaofei; Chen, Shuyan; Zhao, Xinyu; Chen, Wei; Jia, Jidong; Schuppan, Detlef; You, Hong
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001715
-
FYN/LCK kinase balance as a metabolic switch orchestrates progenitor-exhausted T-cell differentiation in hepatocellular carcinom
Author: Wu, Junyu; Jiang, Zhuofeng; Li, Qiucheng; Cheng, Chien-Shan; Chan, Yau-Tuen; Yeerken, Ranna; Chen, Junbang; Lu, Pengde; Feng, Zixin; Yuan, Hongchao; Xu, Lin; Meng, Zhiqiang; Feng, Yibin; Tan, Hor-Yue; Wang, Ning
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001740
-
Liver transcriptome sequencing contributes to the molecular diagnosis of genetic liver disease
Author: Cheng, Ye; Li, Zhong-Die; Guan, Zhi-Hong; Wang, Li; Qiu, Yi-Ling; Fang, Wei-Yuan; Zhao, Jing; Zhang, Kun; Li, Jia-Qi; Xing, Qing-He; Wang, Jian-She
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001747
-
Toxic lipid-induced epigenetic activation of ICAM1 in liver sinusoidal endothelium regulates myeloid-driven fibro-inflammatory response in MAS
Author: Guo, Qianqian; Satthawiwat, Nantawat; Sano, Akitoshi; Meroueh, Chady; Hamdi, Asma; Dai, Xin; Warasnhe, Khaled; Washington, Alexander M.; Starlinger, Patrick P.; Krivonos, Alex; Cao, Sheng; Kostallari, Enis; Jonker, Johan W.; van de Sluis, Bart; Hamdan, Feda H.; Ibrahim, Samar H
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001742
-
Development and validation of risk stratification models for hepatocellular cancer: A framework from the translational liver cancer consortiu
Author: Kanwal, Fasiha; Feng, Ziding; Hoshida, Yujin; Chhatwal, Jagpreet; Wong, Vincent Wai-Sun; Ioannou, George N.; Nahon, Pierre; Lotter, William; Ning, Jing; Taouli, Bachir; Marquez, Guillermo; Fu, Sidney W.; Singal, Amit G
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001745
-
Pathogenic Ifit1+ neutrophils driven by IRF7 promote liver injury and represent a therapeutic target in acute liver failur
Author: Lu, Yu; Zhang, Yi; Sun, Lina; Gao, Fangyuan; Li, Weiyang; Li, Yanqiu; Zhu, Bingbing; Zeng, Xuanwei; Zhou, Yujia; Feng, Ying; Li, Liying; Wang, Xianbo
Journal: HEPATOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1097/HEP.0000000000001738
