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SOX11-mediated CXCL10/CXCR3 activation promotes neuroendocrine prostate cance
Author: Ding, Hekang; Meng, Qingwei; He, Kun; Chen, Ziqi; Tang, Yi; Yang, Yige; Wang, Xu; Zhao, Bing; Xu, Lingfan
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 5, pp. -. DOI: 10.1016/j.jpet.2026.104320
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Ameliorative effects of NAD plus on D-galactose-induced senescence and susceptibility to Acinetobacter baumannii pneumonia via antioxidant and immune modulatio
Author: Wang, Liping; Dong, Liying; Xia, Xue; Tang, Huaqiao; Cheng, Guoqiang; He, Tiantian; Tang, Daxuan; Zhang, Li
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 4, pp. -. DOI: 10.1016/j.jpet.2026.104314
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Drug-drug interactions of antidepressant ammoxetine mediated by cytochrome P450 2D6 and multidrug and toxin extrusion protein 1: From in vitro mechanistic investigations to in vivo validatio
Author: Hu, Juanwen; Liu, Zhihui; Zhang, Qiannan; Li, Cong; Wu, Xia; Zhang, Wenpeng; Zhang, Youzhi; Zhuang, Xiaomei
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 4, pp. -. DOI: 10.1016/j.jpet.2026.104312
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Targeting cholangiocyte sphingosine-1-phosphate (S1P) receptor 1 signaling alleviates cholestatic liver injury: Mechanistic insight into S1P/phosphorylated signal transducer and activator of transcription 3 axi
Author: Yuan, Zihang; Wang, Jie; Zhang, Haoran; Miao, Yingying; Chai, Yuanyuan; Li, Anqin; Tang, Qianhui; Chen, Qingyu; Zhang, Luyong; Yu, Qinwei; Jiang, Zhenzhou
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 4, pp. -. DOI: 10.1016/j.jpet.2026.104306
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Multiomics and experimental validation reveal theophylline's mechanism targeting IL1A/ACTB/TLR4 and identify synergistic drugs in hepatocellular carcinom
Author: Gao, Yuxiang; Chen, Wei; Zarogoulidis, Paul; Yallapu, Murali M.; V. Nikolic, Milos; Vaishnani, Deep K.; Zheng, Jianjian; Nedeljkovic, Nikola; Ye, Kexin; Guo, Yong; Xu, Qiyu
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 3, pp. -. DOI: 10.1016/j.jpet.2026.103836
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Potassium 2-(1-hydroxypentyl)-benzoate improves memory deficits and attenuates amyloid and τ pathologies in a mouse model of Alzheimer's disease (vol. 350, pg. 361, 2014
Author: Peng, Ying; Hu, Yanli; Xu, Shaofeng; Rong, Xianfang; Li, Jiang; Li, Pingping; Wang, Ling; Yang, Jinghua; Wang, Xiaoliang
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 1, pp. -. DOI: 10.1016/j.jpet.2025.103763
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Salusin a counteracts salusin 3 to attenuate artery medial calcification through the inhibition of oxidative stress and extracellular signal-regulated protein kinases signaling pathway in rats with chronic kidney diseas
Author: Gao, Qing; Wang, Mei; Cao, Wen-Juan; Xia, Chen-Xi; Zhu, Han-Xu; Tang, Rong-Jie; Zhou, Ye-Bo; Chen, Lei-Lei
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2026; Vol. 393, Issue 1, pp. -. DOI: 10.1016/j.jpet.2025.103793
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Alleviation of metabolic dysfunction-associated steatotic liver disease by silymarin is associated with maintaining mitochondrial homeostasis via regulation of optic atrophy
Author: Liu, Ming-qiang; Wu, Yuan; Li, Ye; Wei, Yan-bo; Dong, Ling-yue; An, Wei
Journal: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2025; Vol. 392, Issue 7, pp. -. DOI: 10.1016/j.jpet.2025.103611
