| Ocular Drug Delivery: Present Innovations and Future Challenges |
29 |
| Ferroptosis as a Novel Therapeutic Target for Friedreich's Ataxia |
23 |
| Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy Modulation |
20 |
| Binding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the alpha(2)delta Subunit of Voltage-Gated Calcium Channels |
18 |
| Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis |
18 |
| Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy |
18 |
| Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: SLC-Phenotyping Using Primary Human Hepatocytes |
15 |
| Sex Differences in the Pharmacokinetics of Low-dose Ketamine in Plasma and Brain of Male and Female Rats |
15 |
| Pharmacological Evaluation of Dotinurad, a Selective Urate Reabsorption Inhibitor |
14 |
| Organic Anion Transporter 2-Mediated Hepatic Uptake Contributes to the Clearance of High-Permeability-Low-Molecular-Weight Acid and Zwitterion Drugs: Evaluation Using 25 Drugs |
14 |
| SEP-36 a Novel Psychotropic Agent with a Unique, Non-D-2 Receptor Mechanism of Action |
14 |
| Characterization of the Neurochemical and Behavioral Effects of Solriamfetol (JZP-110), a Selective Dopamine and Norepinephrine Reuptake Inhibitor |
14 |
| In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment of Major Depressive Disorder |
13 |
| Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents |
13 |
| Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases |
13 |
| Pharmacologic Characterization of ALD a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide |
13 |
| Mitochondrial Complex I Inhibition by Metformin Limits Reperfusion Injury |
13 |
| Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma |
13 |
| Synthetic Cannabinoid Hydroxypentyl Metabolites Retain Efficacy at Human Cannabinoid Receptors |
13 |
| The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses |
13 |
| Microneedle Coating Methods: A Review with a Perspective |
12 |
| Pharmacological Characterization of IW- a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease |
12 |
| Gellan Gum Based Sol-to-Gel Transforming System of Natamycin Transfersomes Improves Topical Ocular Delivery |
12 |
| Epigenetic Histone Deacetylation Inhibition Prevents the Development and Persistence of Temporal Lobe Epilepsy |
12 |
| A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats |
12 |
| Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy |
11 |
| Establishing Transcriptional Signatures to Differentiate PXR CAR and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes |
11 |
| The Selective Sphingosine 1-Phosphate Receptor Modulator Etrasimod Regulates Lymphocyte Trafficking and Alleviates Experimental Colitis |
10 |
| Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure |
10 |
| The Phosphate Binder Ferric Citrate Alters the Gut Microbiome in Rats with Chronic Kidney Disease |
10 |
| Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis |
10 |
| Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy |
9 |
| Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 |
9 |
| Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy |
9 |
| Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061 |
9 |
| MicroRNA-Directed Cancer Therapies: Implications in Melanoma Intervention |
9 |
| The HNF1 alpha-Regulated LncRNA HNF1 alpha-AS1 Is Involved in the Regulation of Cytochrome P450 Expression in Human Liver Tissues and Huh7 Cells |
9 |
| Plasma and Brain Concentrations of Doxycycline after Single and Repeated Doses in Wild-Type and APP23 Mice |
9 |
| Is There Sufficient Evidence that the Melatonin Binding Site MT3 Is Quinone Reductase 2? |
9 |
| Nose-to-Brain Delivery |
9 |
| Tegoprazan, a Novel Potassium-Competitive Acid Blocker to Control Gastric Acid Secretion and Motility |
8 |
| A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells |
8 |
| Anticancer Activity of Natural and Synthetic Capsaicin Analogs |
8 |
| Predictive Value of Parkinsonian Primates in Pharmacologic Studies: A Comparison between the Macaque, Marmoset, and Squirrel Monkey |
8 |
| Neutral Sphingomyelinase Inhibition Alleviates LPS-Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury |
8 |
| Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress |
8 |
| Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice |
8 |
| Empagliflozin, an SGLT2 Inhibitor, Reduced the Mortality Rate after Acute Myocardial Infarction with Modification of Cardiac Metabolomes and Antioxidants in Diabetic Rats |
8 |
| Long-Lasting Effects of Methocinnamox on Opioid Self-Administration in Rhesus Monkeys |
8 |
| Comprehensive Evaluation of the Utility of 20 Endogenous Molecules as Biomarkers of OATP1B Inhibition Compared with Rosuvastatin and Coproporphyrin I |
8 |
