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Exploring NiCl2, PdCl2 and PtCl2 as a catalyst for [3+2] cycloaddition in Kopsane alkaloid synthesis by density functional theory stud
Author: Yoon, Sanghee; Nakliang, Pratanphorn; Shaker, Bilal; Ye, Tao; Choi, Sun
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. 35, Issue 4, pp. 784-791. DOI: 10.1007/s00044-026-03556-z
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Current CMC challenges in oligonucleotide API development: from IND to ND
Author: Chen, Daoqian; Zhang, Xiaobing; Xu, Songgen; Liu, Deming
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. 35, Issue 4, pp. 711-725. DOI: 10.1007/s00044-026-03569-8
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Proangiogenic effect and molecular mechanism of a new cytosporin derivative from the marine fungus Eutypella sp. D-
Author: Sun, Xiaoyue; Zhu, Ranran; Feng, Qijia; Li, Peihai; Zhang, Yun; Xia, Qing; Liu, Kechun; Jian, Xuehui; Yu, Yuanshuai; Wang, Xue; Sun, Chen; Yu, Haobing
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. , Issue , pp. -. DOI: 10.1007/s00044-026-03548-z
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Synthesis and antihepatoma activity of dimeric 1-O-acetylbritannilactone derivative
Author: Du, Guang-Xuan; He, Li-Qin; Qin, Meng-Xiang; Ma, Yun-Bao; Huang, Xiao-Yan; Wang, Yong-Cui; Li, Tian-Ze; Chen, Ji-Jun
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. , Issue , pp. -. DOI: 10.1007/s00044-026-03558-x
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A comprehensive review of 11C-, 18F-, and 123/124/125I-labeled radiotracers targeting cyclooxygenase-2 over the past two decade
Author: Jia, Jianhua
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. , Issue , pp. -. DOI: 10.1007/s00044-026-03570-1
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Design, synthesis, biological evaluation, and computational studies of chalcone scaffolds as cholinesterase inhibitor
Author: Zhou, Xue-Wei; Wang, Yi-Xuan; Du, Wen-Rong; Zhang, Chao-Yue; Qin, Shi-Hao; Ma, Zheng-Yue
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. , Issue , pp. -. DOI: 10.1007/s00044-026-03536-3
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Inactivation of ornithine aminotransferase by (1R,4S)-4-Amino-3-(trifluoromethyl)cyclopent-2-ene-1-carboxylic acid via a stable quinonoid intermediat
Author: Kang, Koon Mook; Vargas, Abigail L.; Zhu, Wei; Sokolenko, Inna; Liu, Dali; Silverman, Richard B
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. , Issue , pp. -. DOI: 10.1007/s00044-026-03538-1
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Site-Specific incorporation of lysine acetyl-methylation into protein
Author: Zhao, Jingxiang; Guo, Xinlong; Ren, Xuelian; Yu, Jiyang; Song, Xiaohan; Huang, He
Journal: MEDICINAL CHEMISTRY RESEARCH. 2026; Vol. , Issue , pp. -. DOI: 10.1007/s00044-026-03544-3
