Toxicology In Vitro

Toxicology In Vitro

体外毒理学

  • 3区 中科院分区
  • Q3 JCR分区

高引用文章

文章名称 引用次数
In vitro to in vivo extrapolation for high throughput prioritization and decision making 28
Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway 25
Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions 22
A 3D human placenta-on-a-chip model to probe nanoparticle exposure at the placental barrier 19
Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro 15
Preventive effect of TiO2 nanoparticles on heavy metal Pb-induced toxicity, in human lung epithelial (A549) cells 14
Cytotoxicity and cellular mechanisms of toxicity of CuO NPs in mussel cells in vitro and comparative sensitivity with human cells 13
A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme 13
Milan winter fine particulate matter (wPM2.5) induces IL-6 and IL-8 synthesis in human bronchial BEAS-2B cells, but specifically impairs IL-8 release 13
Cytotoxicity of universal dental adhesive systems: Assessment in vitro assays on human gingival fibroblasts 12
Comparison of different cytotoxicity assays for in vitro evaluation of mesoporous silica nanoparticles 12
Monte Carlo based modelling approach for designing and predicting cytotoxicity of 2-phenylindole derivatives against breast cancer cell line MCF7 11
ERK1/2 MAPK promotes autophagy to suppress ER stress-mediated apoptosis induced by cadmium in rat proximal tubular cells 11
Selenium and zinc: Two key players against cadmium-induced neuronal toxicity 11
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies 11
Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity 11
Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models 11
Endocrine disruptor effect of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) on porcine ovarian cell steroidogenesis 11
Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution 11
Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress 10
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 10
Apoptotic and antiproliferative effects of Stigmast-5-en-3-ol from Dendronephthya gigantea on human leukemia HL-60 and human breast cancer MCF-7 cells 10
Anticancer mechanism of troxerutin via targeting Nrf2 and NF-kappa B signalling pathways in hepatocarcinoma cell line 10
Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues - Chlorpyrifos and Carbofuran via oxidative stress 10
Formulants of glyphosate-based herbicides have more deleterious impact than glyphosate on TM4 Sertoli cells 10
MPA-modified CdTe quantum dots increased interleukin-1beta secretion through MyD88-dependent Toll-like receptor pathway and NLRP3 inflammasome activation in microglia 10
VIVD: Virtual in vitro distribution model for the mechanistic prediction of intracellular concentrations of chemicals in in vitro toxicity assays 9
Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells 9
Pre-validation of an in vitro skin irritation test for medical devices using the reconstructed human tissue model EpiDerm (TM) 9
Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer 9
Copper-induced apoptosis and autophagy through oxidative stress-mediated mitochondrial dysfunction in male germ cells 9
Toxicological effects of regulated mycotoxins and persistent organochloride pesticides: In vitro cytotoxic assessment of single and defined mixtures on MA-10 murine Leydig cell line 9
Phenylpropanoid-based sulfonamide promotes cyclin D1 and cyclin E down-regulation and induces cell cycle arrest at G1/S transition in estrogen positive MCF-7 cell line 9
An approach to testing undiluted e-cigarette aerosol in vitro using 3D reconstituted human airway epithelium 9
Immunostimulatory effect of Zinc Phthalocyanine derivatives on macrophages based on the pro-inflammatory TNF alpha and IL1 beta cytokine production levels 9
Zearalenone causes embryotoxicity and induces oxidative stress and apoptosis in differentiated human embryonic stem cells 9
Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study 8
Overexpression of HIF-1a could partially protect K562 cells from 4-benzoquinone induced toxicity by inhibiting ROS, apoptosis and enhancing glycolysis 8
Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice 8
Acute effects of lead on porcine neonatal Sertoli cells in vitro 8
Aspalathin ameliorates doxorubicin-induced oxidative stress in H9c2 cardiomyoblasts 8
Silver nanoparticles induce lysosomal-autophagic defects and decreased expression of transcription factor EB in A549 human lung adenocarcinoma cells 8
Circulatory heavy metals (cadmium, lead, mercury, and chromium) inversely correlate with plasma GST activity and GSH level in COPD patients and impair NOX4/Nrf2/GCLC/GST signaling pathway in cultured monocytes 8
Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes 8
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells 8
Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells 8
Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment 8
Biocompatibility of pristine graphene monolayer: Scaffold for fibroblasts 8
Antiparasitic, structural, pharmacokinetic, and toxicological properties of riparin derivatives 8
In vitro percutaneous absorption and metabolism of Bisphenol A (BPA) through fresh human skin 8