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Surface-water estradiol-benzo[a]pyrene mixtures: Transcriptomics in a PC12 neuronal differentiation model nominate an E2F1-PTPRO axis as a candidate mechanistic biomarke
Author: Sun, Caiyun; Wang, Peng; Xia, Yu; An, Mengyuan; Liu, Shuang; Wu, Chuanbing; Zhang, Wansheng; Li, Wenwen; Zhou, Yuhan; Hao, Junkai; Xu, Liang
Journal: TOXICOLOGY LETTERS. 2026; Vol. 419, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111882
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Deoxynivalenol-induced hepatic and renal injury via pyroptosis under heat stress condition
Author: Zhang, Jingdi; Rafique, Amna; Liu, Jie; Saqlain, Muhammad; Yang, Bo; Zhang, Ding; Niu, Ruiyan; Sun, Zilong
Journal: TOXICOLOGY LETTERS. 2026; Vol. 419, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111888
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Chronic exposure to F-53B disrupts sperm quality and steroidogenic regulation in male rat
Author: Wang, Xueying; Wang, Aiqing; Xu, Hao; Shan, Shan; Li, Xiaohan; Zhang, Yan; Wang, Jun; Jiang, Kexin; Tian, Hailin; Zhao, Yun
Journal: TOXICOLOGY LETTERS. 2026; Vol. 419, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111885
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Targeting PCSK9 suppresses NF-κB-mediated M1 polarization in alveolar macrophages and lung injury induced by low-dose systemic PM2.5 exposur
Author: Wang, Chenxi; Zhang, Weichao; Liu, Yanjun; Guo, Yangyang
Journal: TOXICOLOGY LETTERS. 2026; Vol. 419, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111887
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Tripchlorolide-induced reversible impairment of male fertility and the involvement of PI3K/Akt/mTOR signalin
Author: Zhou, Lele; Chen, Lingbin; Zheng, Cailin; Wu, Jinneng; Zhong, Meihua; Huang, Zhixiong; Xin, Zhiming; Chen, Zhou
Journal: TOXICOLOGY LETTERS. 2026; Vol. 419, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111872
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Advances in aluminum oxide nanoparticles-induced neurotoxicity: CNS translocation, phenotypic outcomes, and mechanistic insight
Author: Yu, Lei; Rana, Mohammad Nasiruddin; Quan, Changjian; Zhou, Zhen; Chen, Zhaojun; Gao, Xiangjing; Gao, Xiangwei
Journal: TOXICOLOGY LETTERS. 2026; Vol. 419, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111873
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Histone H3K4 monomethyltransferase SETD7 promoted osteogenic differentiation of bone marrow mesenchymal stem cells exposed to Hydroquinone via autophag
Author: Shen, Yilin; Niu, Yibo; Xu, Tao; Luo, Zhilong; Song, Donghao; Luo, Chiheng; Liu, Yan; Cui, Qilin; Chen, Dongxiao; Zhao, Xinyu; Luo, Hao; Gao, Yuting
Journal: TOXICOLOGY LETTERS. 2026; Vol. 418, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111863
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Excessive fluoride induces renal cell apoptosis and subsequent renal dysfunctio
Author: Zhang, Yi; Xu, Zhao; Xie, Pengpeng; Xiao, Yating; Dong, Siyuan; Chen, Chen; Chen, Qun
Journal: TOXICOLOGY LETTERS. 2026; Vol. 418, Issue , pp. -. DOI: 10.1016/j.toxlet.2026.111862