| Unconventional superconductivity in magic-angle graphene superlattices |
875 |
| Perovskite light-emitting diodes with external quantum efficiency exceeding 20 per cent |
573 |
| Correlated insulator behaviour at half-filling in magic-angle graphene superlattices |
545 |
| Efficient, stable and scalable perovskite solar cells using poly(3-hexylthiophene) |
530 |
| Quantum supremacy using a programmable superconducting processor |
474 |
| The UK Biobank resource with deep phenotyping and genomic data |
431 |
| TGF beta attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells |
395 |
| Search-and-replace genome editing without double-strand breaks or donor DNA |
373 |
| The biology and management of non-small cell lung cancer |
371 |
| Machine learning for molecular and materials science |
363 |
| Perovskite light-emitting diodes based on spontaneously formed submicrometre-scale structures |
341 |
| Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
338 |
| Skin electronics from scalable fabrication of an intrinsically stretchable transistor array |
289 |
| Environment dominates over host genetics in shaping human gut microbiota |
282 |
| Maximizing and stabilizing luminescence from halide perovskites with potassium passivation |
276 |
| Gate-tunable room-temperature ferromagnetism in two-dimensional Fe3GeTe2 |
270 |
| DNA methylation-based classification of central nervous system tumours |
266 |
| Options for keeping the food system within environmental limits |
261 |
| RNA velocity of single cells |
251 |
| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 |
247 |
| Planar perovskite solar cells with long-term stability using ionic liquid additives |
231 |
| TGF beta drives immune evasion in genetically reconstituted colon cancer metastasis |
230 |
| A library of atomically thin metal chalcogenides |
230 |
| Deep learning and process understanding for data-driven Earth system science |
216 |
| Single-cell reconstruction of the early maternal-fetal interface in humans |
215 |
| Efficient and stable emission of warm-white light from lead-free halide double perovskites |
213 |
| Extensive impact of non-antibiotic drugs on human gut bacteria |
212 |
| Approaching the Schottky-Mott limit in van der Waals metal-semiconductor junctions |
210 |
| Small-scale soft-bodied robot with multimodal locomotion |
208 |
| Next-generation characterization of the Cancer Cell Line Encyclopedia |
207 |
| Global warming transforms coral reef assemblages |
206 |
| Printing ferromagnetic domains for untethered fast-transforming soft materials |
206 |
| Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults |
205 |
| Integrated lithium niobate electro-optic modulators operating at CMOS-compatible voltages |
201 |
| The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity |
200 |
| A rigorous electrochemical ammonia synthesis protocol with quantitative isotope measurements |
197 |
| Evolved Cas9 variants with broad PAM compatibility and high DNA specificity |
197 |
| Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris |
186 |
| Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial |
186 |
| Identification of the tumour transition states occurring during EMT |
184 |
| All-inorganic perovskite nanocrystal scintillators |
183 |
| Evidence for moire excitons in van der Waals heterostructures |
183 |
| Global land change from 1982 to 2016 |
181 |
| High performance plasma amyloid-beta biomarkers for Alzheimer's disease |
180 |
| Superconductors, orbital magnets and correlated states in magic-angle bilayer graphene |
180 |
| Thickness - independent capacitance of vertically aligned liquid-crystalline MXenes |
178 |
| Image reconstruction by domain-transform manifold learning |
178 |
| A molecular atlas of cell types and zonation in the brain vasculature |
177 |
| Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases |
176 |
| Single-cell transcriptomic analysis of Alzheimer's disease |
175 |
| Magnetism in two-dimensional van der Waals materials |
173 |
| Planning chemical syntheses with deep neural networks and symbolic AI |
171 |
| The landscape of genomic alterations across childhood cancers |
165 |
| The single-cell transcriptional landscape of mammalian organogenesis |
164 |
| Mapping the world's free-flowing rivers |
163 |
| Van der Waals integration before and beyond two-dimensional materials |
163 |
| Genetic compensation triggered by mutant mRNA degradation |
162 |
| Signatures of moire-trapped valley excitons in MoSe2/WSe2 heterobilayers |
159 |
| Observation of moire excitons in WSe2/WS2 heterostructure superlattices |
159 |
| Temporal development of the gut microbiome in early childhood from the TEDDY study |
158 |
| Superconductivity at 250 K in lanthanum hydride under high pressures |
155 |
| Bystander CD8(+) T cells are abundant and phenotypically distinct in human tumour infiltrates |
155 |
| Processing bulk natural wood into a high-performance structural material |
155 |
| Advanced maturation of human cardiac tissue grown from pluripotent stem cells |
154 |
| Structure and function of the global topsoil microbiome |
154 |
| Parkin and PINK1 mitigate STING-induced inflammation |
153 |
| FSP1 is a glutathione-independent ferroptosis suppressor |
148 |
| Meta-analysis and the science of research synthesis |
148 |
| Enhanced strength and ductility in a high-entropy alloy via ordered oxygen complexes |
148 |
| Emerging trends in global freshwater availability |
146 |
| Triggers of tree mortality under drought |
145 |
| Neutrophils escort circulating tumour cells to enable cell cycle progression |
144 |
| Genomic variation in 010 diverse accessions of Asian cultivated rice |
144 |
| Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution |
142 |
| Conserved cell types with divergent features in human versus mouse cortex |
139 |
| A revised airway epithelial hierarchy includes CFTR-expressing ionocytes |
139 |
| A new genomic blueprint of the human gut microbiota |
137 |
| Multi-terminal memtransistors from polycrystalline monolayer molybdenum disulfide |
137 |
| The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis |
135 |
| Bright triplet excitons in caesium lead halide perovskites |
135 |
| Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline |
135 |
| Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH |
135 |
| A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte |
134 |
| PdMo bimetallene for oxygen reduction catalysis |
134 |
| Self-powered ultra-flexible electronics via nano-grating-patterned organic photovoltaics |
134 |
| Genomic atlas of the human plasma proteome |
133 |
| A complete catalogue of high-quality topological materials |
132 |
| An absorption profile centred at 78 megahertz in the sky-averaged spectrum |
131 |
| Shared and distinct transcriptomic cell types across neocortical areas |
131 |
| Majorana quantization and half-integer thermal quantum Hall effect in a Kitaev spin liquid |
130 |
| The merger that led to the formation of the Milky Way's inner stellar halo and thick disk |
129 |
| Chromosomal instability drives metastasis through a cytosolic DNA response |
128 |
| Maximized electron interactions at the magic angle in twisted bilayer graphene |
127 |
| Incompatible and sterile insect techniques combined eliminate mosquitoes |
127 |
| Functional genomic landscape of acute myeloid leukaemia |
127 |
| Solution-processable 2D semiconductors for high-performance large-area electronics |
127 |
| Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens |
127 |
| A defined commensal consortium elicits CD8 T cells and anti-cancer immunity |
126 |
| A randomized trial of normothermic preservation in liver transplantation |
125 |
| Prediction of acute myeloid leukaemia risk in healthy individuals |
125 |
| Quantifying inactive lithium in lithium metal batteries |
125 |
| Structures of filaments from Pick's disease reveal a novel tau protein fold |
124 |
| TOX transcriptionally and epigenetically programs CD8(+) T cell exhaustion |
124 |
| Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin |
124 |
| Recycling lithium-ion batteries from electric vehicles |
124 |
| Equivalent-accuracy accelerated neural-network training using analogue memory |
123 |
| Actively personalized vaccination trial for newly diagnosed glioblastoma |
123 |
| Mass balance of the Antarctic Ice Sheet from 1992 to 2017 |
122 |
| Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease |
122 |
| Arthropod decline in grasslands and forests is associated with landscape-level drivers |
122 |
| Observation of a phononic quadrupole topological insulator |
122 |
| Resonantly hybridized excitons in moire superlattices in van der Waals heterostructures |
121 |
| Prediction and observation of an antiferromagnetic topological insulator |
120 |
| An 800-million-solar-mass black hole in a significantly neutral Universe at a redshift of 7.5 |
120 |
| Aqueous Li-ion battery enabled by halogen conversion-intercalation chemistry in graphite |
120 |
| Quantized Majorana conductance |
119 |
| Human placenta has no microbiome but can contain potential pathogens |
119 |
| Cryo-STEM mapping of solid-liquid interfaces and dendrites in lithium-metal batteries |
118 |
| Integrating photonics with silicon nanoelectronics for the next generation of systems on a chip |
118 |
| A clinically applicable approach to continuous prediction of future acute kidney injury |
118 |
| Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma |
117 |
| New mitochondrial DNA synthesis enables NLRP3 inflammasome activation |
117 |
| Catalogue of topological electronic materials |
117 |
| L1 drives IFN in senescent cells and promotes age-associated inflammation |
116 |
| Highly efficient and stable InP/ZnSe/ZnS quantum dot light-emitting diodes |
115 |
| El Nino-Southern Oscillation complexity |
115 |
| Superconductivity in an infinite-layer nickelate |
114 |
| Individual brain organoids reproducibly form cell diversity of the human cerebral cortex |
114 |
| A quantized microwave quadrupole insulator with topologically protected corner states |
113 |
| Amino-acid- and peptide-directed synthesis of chiral plasmonic gold nanoparticles |
113 |
| HER kinase inhibition in patients with HER2-and HER3-mutant cancers |
112 |
| NLRP3 inflammasome activation drives tau pathology |
111 |
| Improved limit on the electric dipole moment of the electron |
111 |
| Niobium tungsten oxides for high-rate lithium-ion energy storage |
111 |
| A view on drug resistance in cancer |
110 |
| Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules |
110 |
| CD8(+) T cells regulate tumour ferroptosis during cancer immunotherapy |
109 |
| Genetic and transcriptional evolution alters cancer cell line drug response |
108 |
| Graphene and two-dimensional materials for silicon technology |
108 |
| The Moral Machine experiment |
108 |
| Subwavelength integrated photonics |
108 |
| Observed fingerprint of a weakening Atlantic Ocean overturning circulation |
107 |
| Reversible Mn2+/Mn4+ double redox in lithium-excess cathode materials |
107 |
| TOX is a critical regulator of tumour-specific T cell differentiation |
106 |
| Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance |
106 |
| A global map of travel time to cities to assess inequalities in accessibility in 2015 |
105 |
| One thousand plant transcriptomes and the phylogenomics of green plants |
105 |
| Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells |
105 |
| Autophagy induction via STING trafficking is a primordial function of the cGAS pathway |
105 |
| Senescence-associated reprogramming promotes cancer stemness |
105 |
| Global glacier mass changes and their contributions to sea-level rise from 1961 to 2016 |
105 |
| Microglial control of astrocytes in response to microbial metabolites |
104 |
| A programmable two-qubit quantum processor in silicon |
103 |
| Genome evolution across 011 Saccharomyces cerevisiae isolates |
103 |
| Mapping human microbiome drug metabolism by gut bacteria and their genes |
103 |
| Comprehensive search for topological materials using symmetry indicators |
103 |
| CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy |
102 |
| Advances in epigenetics link genetics to the environment and disease |
101 |
| Neoantigen-directed immune escape in lung cancer evolution |
101 |
| A human liver cell atlas reveals heterogeneity and epithelial progenitors |
101 |
| Signatures of tunable superconductivity in a trilayer graphene moire superlattice |
100 |
| HIV-1 remission following CCR5 Delta 32/Delta 32 haematopoietic stem-cell transplantation |
100 |
| Epitaxial growth of a 100-square-centimetre single-crystal hexagonal boron nitride monolayer on copper |
100 |
| Charge order and broken rotational symmetry in magic-angle twisted bilayer graphene |
100 |
| Spectroscopic signatures of many-body correlations in magic-angle twisted bilayer graphene |
99 |
| Pursuing sustainable productivity with millions of smallholder farmers |
99 |
| Sensitive tumour detection and classification using plasma cell-free DNA methylomes |
99 |
| Targeted neurotechnology restores walking in humans with spinal cord injury |
99 |
| Genome-wide cell-free DNA fragmentation in patients with cancer |
98 |
| Highly structured slow solar wind emerging from an equatorial coronal hole |
96 |
| From discoveries in ageing research to therapeutics for healthy ageing |
96 |
| Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors |
96 |
| All-optical spiking neurosynaptic networks with self-learning capabilities |
96 |
| The human gut microbiome in early-onset type 1 diabetes from the TEDDY study |
95 |
| Tuning element distribution, structure and properties by composition in high-entropy alloys |
95 |
| Ketamine blocks bursting in the lateral habenula to rapidly relieve depression |
95 |
| Changing climate both increases and decreases European river floods |
95 |
| Ultra-large library docking for discovering new chemotypes |
95 |
| Visualizing vibrational normal modes of a single molecule with atomically confined light |
95 |
| Managing nitrogen to restore water quality in China |
95 |
| TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection |
94 |
| Topological band engineering of graphene nanoribbons |
94 |
| Resolving the fibrotic niche of human liver cirrhosis at single-cell level |
94 |
| Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis |
94 |
| The evolutionary history of vertebrate RNA viruses |
94 |
| The bone marrow microenvironment at single-cell resolution |
93 |
| Efficient radical-based light-emitting diodes with doublet emission |
93 |
| Accurate classification of BRCA1 variants with saturation genome editing |
93 |
| Enhancing the potential of enantioselective organocatalysis with light |
93 |
| China's response to a national land-system sustainability emergency |
92 |
| Future response of global coastal wetlands to sea-level rise |
92 |
| A fast radio burst localized to a massive galaxy |
90 |
| Innate immune memory in the brain shapes neurological disease hallmarks |
90 |
| Electrical and synaptic integration of glioma into neural circuits |
90 |
| Scalable energy-efficient magnetoelectric spin-orbit logic |
90 |
| Structure of the mu-opioid receptor-G(i) protein complex |
90 |
| Cellular milieu imparts distinct pathological alpha-synuclein strains in alpha-synucleinopathies |
90 |
| MHC-II neoantigens shape tumour immunity and response to immunotherapy |
89 |
| Overcoming the rate-distance limit of quantum key distribution without quantum repeaters |
89 |
| Marine heatwaves under global warming |
89 |
